Clonal development from a progenitor with restricted differentiative expression in acute lymphoblastic leukemia

A. M. Ferraris, L. Canepa, L. Massimo, G. Dini, G. Broccia, T. Meloni, G. Forteleoni, C. Melani, G. F. Gaetani

Research output: Contribution to journalArticlepeer-review

Abstract

Three patients with acute lymphoblastic leukemia (ALL) and heterozygous for the Mediterranean variant of glucose-6-phosphate dehydrogenase (G6PD) have been investigated with the 2-deoxyglucose-6-phosphate (2dG6P) method to determine the number and type of progenitor cells in which the disease arose. A monoclonal origin was established for the lymphoblasts, while the other hemopoietic cell lines were not involved in the leukemic process.

Original languageEnglish
Pages (from-to)81-83
Number of pages3
JournalAmerican Journal of Hematology
Volume20
Issue number1
DOIs
Publication statusPublished - 1985

ASJC Scopus subject areas

  • Hematology

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