Clonidine for neonates receiving mechanical ventilation

Olga Romantsik, Maria Grazia Calevo, Elisabeth Norman, Matteo Bruschettini

Research output: Contribution to journalArticlepeer-review


This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess whether clonidine infusion in term and preterm newborn infants receiving mechanical ventilation reduces the rate of mortality and morbidity. The intervention will be compared to placebo, no treatment and dexmedetomidine. In addition, the safety of clonidine infusion will be assessed for potential harms. We will perform subgroup analyses according to gestational age; birth weight; dose, duration and route of clonidine administration; and presence of pharmacological sedation as co-intervention.

Original languageEnglish
Article numberCD012468
JournalCochrane Database of Systematic Reviews
Issue number12
Publication statusPublished - Dec 9 2016

ASJC Scopus subject areas

  • Medicine(all)
  • Pharmacology (medical)


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