Abstract
Chronic graft-versus-host disease can mimic various autoimmune disorders, although autoantibodies are rarely detected in the sera of affected patients. Antibodies to cytcskeleton are a frequent finding in patients affected by autoimmune disorders. In all the sera of 16 patients who were submitted to allogeneic bone marrow transplantation, we have found antibodies against cytoskeletai intermediate filaments. Moreover, the titer of such antibodies is quite elevated when compared with those reported in autoimmune disorders. A statistically significant difference between the titers found in patients without and with cGVHD (median 1:40 vs. 1:256, P
Original language | English |
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Pages (from-to) | 234-236 |
Number of pages | 3 |
Journal | Transplantation |
Volume | 44 |
Issue number | 2 |
Publication status | Published - 1987 |
ASJC Scopus subject areas
- Transplantation
- Immunology