TY - JOUR
T1 - Close correlation between anxiety, depression, and asthma control
AU - Di Marco, Fabiano
AU - Verga, Massimo
AU - Santus, Pierachille
AU - Giovannelli, Francesca
AU - Busatto, Paolo
AU - Neri, Margherita
AU - Girbino, Giuseppe
AU - Bonini, Sergio
AU - Centanni, Stefano
PY - 2010/1
Y1 - 2010/1
N2 - Background: We investigated the correlation between patients' characteristics, including anxiety and depression, and the level of asthma control evaluated by asthma control test (ACT), a self-administered validated questionnaire. Methods: This is a cross-sectional study on asthmatic outpatients of three Italian hospitals. Demographic data, spirometry, anxiety and depression scores as well as the level of asthma control from 315 patients were collected. Results: Patients with poorly controlled asthma were more frequently women, older, with a worse pulmonary function, obese, more anxious and/or more depressed. Four different independent factors associated with poor asthma control evaluated by ACT have been found: FEV1 <60% (odds ratio, OR: 6.52), anxiety (OR: 3.76), age ≥65 years (OR: 2.69), and depression (OR: 2.45). The presence of anxiety and depression was associated with a higher healthcare utilization. Finally, we found a high level of agreement between ACT and multidimensional GINA approach in evaluating asthma control, with a concordance in 239 patients (81% of the population). Conclusion: There is a close correlation between anxiety and depression, and a poor asthma. A better understanding of this association may have major clinical implications, mainly in patients with poor controlled asthma in whom the presence of anxiety and depression should be investigated.
AB - Background: We investigated the correlation between patients' characteristics, including anxiety and depression, and the level of asthma control evaluated by asthma control test (ACT), a self-administered validated questionnaire. Methods: This is a cross-sectional study on asthmatic outpatients of three Italian hospitals. Demographic data, spirometry, anxiety and depression scores as well as the level of asthma control from 315 patients were collected. Results: Patients with poorly controlled asthma were more frequently women, older, with a worse pulmonary function, obese, more anxious and/or more depressed. Four different independent factors associated with poor asthma control evaluated by ACT have been found: FEV1 <60% (odds ratio, OR: 6.52), anxiety (OR: 3.76), age ≥65 years (OR: 2.69), and depression (OR: 2.45). The presence of anxiety and depression was associated with a higher healthcare utilization. Finally, we found a high level of agreement between ACT and multidimensional GINA approach in evaluating asthma control, with a concordance in 239 patients (81% of the population). Conclusion: There is a close correlation between anxiety and depression, and a poor asthma. A better understanding of this association may have major clinical implications, mainly in patients with poor controlled asthma in whom the presence of anxiety and depression should be investigated.
KW - Anxiety
KW - Asthma
KW - Asthma control
KW - Depression
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U2 - 10.1016/j.rmed.2009.08.005
DO - 10.1016/j.rmed.2009.08.005
M3 - Article
C2 - 19733042
AN - SCOPUS:74149092449
VL - 104
SP - 22
EP - 28
JO - Respiratory Medicine
JF - Respiratory Medicine
SN - 0954-6111
IS - 1
ER -