Closer to the gold standard: An appraisal of formulae available in Italy for use in formula-fed infants

Enrica Riva, E. Verduci, C. Agostoni, M. Giovannini

Research output: Contribution to journalArticlepeer-review

Abstract

Infant formulae are the only alternatives to breast milk for infants who are unable to continue breastfeeding through the first year of life. They aim to provide formula-fed infants with the same structural and functional benefits observed in breastfed infants. To achieve this, bioactive nutrients have been added to infant formulae in recent years: long-chain polyunsaturated fatty acids for neurodevelopment; probiotics and prebiotics for local gastrointestinal defence; and nucleotides for promoting the immune response. Changes in protein quantity and quality allow infant formulae to achieve a balance between providing the correct plasma amino acid profile and reducing the protein intake, which could prevent obesity in later life. Hydrolysed proteins may help prevent atopic disorders. Many short-term trials have been published but long-term follow-up data are needed in infants who have been fed the newer infant formulae, to fully understand the role of bioactive nutrients.

Original languageEnglish
Pages (from-to)595-611
Number of pages17
JournalJournal of International Medical Research
Volume33
Issue number6
Publication statusPublished - Nov 2005

Keywords

  • Bioactive nutrients
  • Infant formula
  • Long-chain polyunsaturated fatty acids
  • Prebiotics
  • Probiotics

ASJC Scopus subject areas

  • Medicine(all)

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