Abstract
In rat intestinal crypt cells, Clostridium difficile toxin A induces (i) early cytoskeletal alterations involving the whole population and (ii) late effects in 30 to 40% of the cells, consisting mainly of surface blebbing and nuclear fragmentation. All these effects were Ca2+ independent and were not abolished by protein synthesis inhibitors.
Original language | English |
---|---|
Pages (from-to) | 3988-3993 |
Number of pages | 6 |
Journal | Infection and Immunity |
Volume | 61 |
Issue number | 9 |
Publication status | Published - 1993 |
ASJC Scopus subject areas
- Immunology