Clozapine and full-dose concomitant chemoradiation therapy in a schizophrenic patient with nasopharyngeal cancer

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Abstract

Clozapine is a neuroleptic drug used in selected schizophrenic patients. Its use is limited because of unpredictable myelotoxicity. The potentially dangerous interaction between cancer treatment and clozapine is virtually unknown. A 37-year-old schizophrenic patient under treatment with clozapine, diagnosed with undifferentiated nasopharyngeal carcinoma, was treated with full-dose cisplatin and concomitant radiotherapy without reporting significant neutropenia. Clozapine may be cautiously administered when full-dose concomitant chemoradiation therapy is required .

Original languageEnglish
Pages (from-to)59-60
Number of pages2
JournalTumori
Volume88
Issue number1
Publication statusPublished - 2002

Keywords

  • Chemoradiation
  • Clozapine
  • Neutropenia

ASJC Scopus subject areas

  • Cancer Research

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