Clues on Balo's concentric sclerosis evolution from serial analysis of ADC values

Paolo Ripellino, Roman Khonsari, Alessandro Stecco, Massimo Filippi, Marco Perchinunno, Roberto Cantello

Research output: Contribution to journalArticlepeer-review

Abstract

Balò's sclerosis is considered a rare variant of multiple sclerosis characterized by demyelination with concentric rings. Advanced magnetic resonance studies allow nowadays early diagnosis and prompt treatment. However, the pathophysiology of lesion evolution is still matter of debate, as detailed in our literature review. Based on a clear-cut Balò's lesion analysis, we describe early changes in DWI and ADC values within the different layers, favoring the concept of a centrifugal growth.

Original languageEnglish
Pages (from-to)88-95
Number of pages8
JournalInternational Journal of Neuroscience
Volume126
Issue number1
DOIs
Publication statusPublished - Jan 2 2016

Keywords

  • ADC
  • Balò's sclerosis
  • concentric sclerosis
  • diffusion
  • MRI

ASJC Scopus subject areas

  • Neuroscience(all)

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