Co-infection in children with bloody diarrhea caused by shiga toxin-producing escherichia coli: Data of the North Italian HUS network

Gianluigi Ardissino, Ilaria Possenti, Stefania Salardi, Francesca Tel, Elisa Colombo, Sara Testa, Laura Daprai, Damiano Picicco, Rosaria Maria Colombo, Erminio Torresani

Research output: Contribution to journalArticle


Hemolytic-uremic syndrome (HUS) is an important cause of acute kidney injury in children often caused by Shiga toxin-producing Escherichia coli (STEC) enterocolitis. In a screening program for STEC infection in children with bloody diarrhea in northern Italy for early diagnosis of HUS, co-infection with Salmonella or Campylobacter was documented in as many as 35.6% of Shiga toxin-positive patients. It is speculated that infection by Salmonella or Campylobacter may increase the risk of STEC enterocolitis and therefore of HUS. The isolation of microorganisms (other then STEC) in HUS should not be necessarily regarded as the etiological agent for the thrombotic microangiopathy.

Original languageEnglish
Pages (from-to)218-220
Number of pages3
JournalJournal of Pediatric Gastroenterology and Nutrition
Issue number2
Publication statusPublished - 2014



  • bloody diarrhea
  • co-infection
  • Shiga toxin-producing Escherichia coli

ASJC Scopus subject areas

  • Gastroenterology
  • Pediatrics, Perinatology, and Child Health
  • Medicine(all)

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