Co-morbidities and quality of life in elderly persons with haemophilia

Massimo Franchini, Pier Mannuccio Mannucci

Research output: Contribution to journalArticle

Abstract

The life expectancy and quality of life of persons with haemophilia has dramatically increased since the 1970s, with the exception of the increased rate of deaths observed during the 1980s and the 1990s due to blood-borne viral infections. Improvements of factor replacement therapy, treatment of infectious diseases and comprehensive health care provided by specialised haemophilia centres are the main determinants of the increasing age of the haemophilia population. As a consequence, a growing number of these patients develop age-related co-morbidities, such as cardiovascular disease and cancer. The care of these previously rare conditions is a new challenge for caregivers in haemophilia centres. This review focuses on co-morbidities in the ageing haemophilia patients, their impact on quality of life and their complex management.

Original languageEnglish
Pages (from-to)522-533
Number of pages12
JournalBritish Journal of Haematology
Volume148
Issue number4
DOIs
Publication statusPublished - Feb 2010

Keywords

  • Ageing
  • Cancer
  • Cardiovascular disease
  • Elderly
  • Haemophilia

ASJC Scopus subject areas

  • Hematology

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