CO2-induced panic attacks: A twin study

Laura Bellodi, Giampaolo Perna, Daniela Caldirola, Cinzia Arancio, Angelo Bertani, Daniela Di Bella

Research output: Contribution to journalArticlepeer-review


Objective: The authors investigated the role of genetic factors in 35% CO2-induced panic attacks. Method: Ninety twins recruited from the general population were challenged with one-vital-capacity inhalations of 35% CO2- 65% O2. Probandwise concordance rates were calculated and rates compared for monozygotic and for dizygotic twins. Results: A significantly higher concordance was found for 35% CO2-induced panic attacks among monozygotic than dizygotic twins (55.6% versus 12.5%). Conclusions: These results suggest a relevant role of genetic factors in 35% CO2-induced panic attacks.

Original languageEnglish
Pages (from-to)1184-1188
Number of pages5
JournalAmerican Journal of Psychiatry
Issue number9
Publication statusPublished - Sep 1998

ASJC Scopus subject areas

  • Psychiatry and Mental health


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