TY - JOUR
T1 - Coagulation and fibrinolysis changes in normal pregnancy increased levels of procoagulants and reduced levels of inhibitors during pregnancy induce a hypercoagulable state, combined with a reactive fibrinolysis
AU - Cerneca, Federico
AU - Ricci, Giuseppe
AU - Simeone, Roberto
AU - Malisano, Monica
AU - Alberico, Salvatore
AU - Guaschino, Seconde
PY - 1997/5
Y1 - 1997/5
N2 - Objective: To establish the physiologic changes in the coagulation and fibrinolytic systems during normal pregnancy and puerperium. Study Design: One hundred and seventeen normal pregnant women were investigated in a longitudinal study involving five measurements: blood samples were collected at 10, 20, 30, 36 weeks and on the second day puerperium and were assayed for prothrombin time (PT expressed in INR), activated partial thromboplastin time (PLY), fibrinogen (FBG), antithrombin III activity (AT III), protein C activity (PC), protein S activity (PS), prothrombin fragments 1+2 (F1 +2), type 1 plasminogen activator inhibitor activity (PAI) and tissue-plasminogen activator antigen (t-PA). Student t-test, One Way Analysis of Variance (ANOVA) and Bonferroni test were used for statistical analysis. P
AB - Objective: To establish the physiologic changes in the coagulation and fibrinolytic systems during normal pregnancy and puerperium. Study Design: One hundred and seventeen normal pregnant women were investigated in a longitudinal study involving five measurements: blood samples were collected at 10, 20, 30, 36 weeks and on the second day puerperium and were assayed for prothrombin time (PT expressed in INR), activated partial thromboplastin time (PLY), fibrinogen (FBG), antithrombin III activity (AT III), protein C activity (PC), protein S activity (PS), prothrombin fragments 1+2 (F1 +2), type 1 plasminogen activator inhibitor activity (PAI) and tissue-plasminogen activator antigen (t-PA). Student t-test, One Way Analysis of Variance (ANOVA) and Bonferroni test were used for statistical analysis. P
KW - Coagulation
KW - Fibrinolysis
KW - Pregnancy
KW - Puerperium
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U2 - 10.1016/S0301-2115(97)02734-6
DO - 10.1016/S0301-2115(97)02734-6
M3 - Article
C2 - 9175686
AN - SCOPUS:0030920155
VL - 73
SP - 31
EP - 36
JO - European Journal of Obstetrics, Gynecology and Reproductive Biology
JF - European Journal of Obstetrics, Gynecology and Reproductive Biology
SN - 0028-2243
IS - 1
ER -