Abstract
Clinical laboratories need to test patient samples precisely, accurately, and efficiently. The latest member of the Roche cobas modular platform family, the cobas 8000 modular analyzer series allows compact and convenient consolidation of clinical chemistry and immunochemistry assays in high-workload laboratories with a throughput of 3 to 15 million tests annually. Here we present the results of studies designed to test the overall system performance under routine-like conditions that were conducted at 14 laboratories over 2 y. Experiments that test analytical performance of the new module were integrated with overall system functionality testing of all modules in different configurations. More than two million results were generated and evaluated for ~100 applications using serum/plasma, urine, or EDTA blood samples. During the workflow studies, eight configurations of the possible 38 combinations were used, covering all available analytical modules. The versatility of the module combinations makes the system customizable to fit the needs of diverse laboratories, allowing precise and accurate analysis of a broad spectrum of clinical chemistry and immunochemistry parameters with short turnaround times. This new system will contribute to the ability of clinical laboratories to offer better service to their customers and support vital clinical decision making.
| Original language | English |
|---|---|
| Pages (from-to) | 306-327 |
| Number of pages | 22 |
| Journal | Journal of laboratory automation |
| Volume | 18 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Mar 2013 |
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Keywords
- analytical modules
- analytical performance
- analyzers
- practicability assessment
- workflow analysis
ASJC Scopus subject areas
- Computer Science Applications
- Medical Laboratory Technology
Cite this
cobas 8000 Modular Analyzer Series Evaluated under Routine-like Conditions at 14 Sites in Australia, Europe, and the United States. / von Eckardstein, Arnold; Roth, Hans Jürgen; Jones, Graham; Preston, Sharon; Szekeres, Thomas; Imdahl, Roland; Conti, Marc; Blanckaert, Norbert; Jose, Darren; Thiery, Joachim; Feldmann, Lisa; von Ahsen, Nicolas; Locatelli, Massimo; Kremastinou, Jenni; Kunst, Albert; Hubbuch, Arnulf; McGovern, Margaret.
In: Journal of laboratory automation, Vol. 18, No. 4, 03.2013, p. 306-327.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - cobas 8000 Modular Analyzer Series Evaluated under Routine-like Conditions at 14 Sites in Australia, Europe, and the United States
AU - von Eckardstein, Arnold
AU - Roth, Hans Jürgen
AU - Jones, Graham
AU - Preston, Sharon
AU - Szekeres, Thomas
AU - Imdahl, Roland
AU - Conti, Marc
AU - Blanckaert, Norbert
AU - Jose, Darren
AU - Thiery, Joachim
AU - Feldmann, Lisa
AU - von Ahsen, Nicolas
AU - Locatelli, Massimo
AU - Kremastinou, Jenni
AU - Kunst, Albert
AU - Hubbuch, Arnulf
AU - McGovern, Margaret
PY - 2013/3
Y1 - 2013/3
N2 - Clinical laboratories need to test patient samples precisely, accurately, and efficiently. The latest member of the Roche cobas modular platform family, the cobas 8000 modular analyzer series allows compact and convenient consolidation of clinical chemistry and immunochemistry assays in high-workload laboratories with a throughput of 3 to 15 million tests annually. Here we present the results of studies designed to test the overall system performance under routine-like conditions that were conducted at 14 laboratories over 2 y. Experiments that test analytical performance of the new module were integrated with overall system functionality testing of all modules in different configurations. More than two million results were generated and evaluated for ~100 applications using serum/plasma, urine, or EDTA blood samples. During the workflow studies, eight configurations of the possible 38 combinations were used, covering all available analytical modules. The versatility of the module combinations makes the system customizable to fit the needs of diverse laboratories, allowing precise and accurate analysis of a broad spectrum of clinical chemistry and immunochemistry parameters with short turnaround times. This new system will contribute to the ability of clinical laboratories to offer better service to their customers and support vital clinical decision making.
AB - Clinical laboratories need to test patient samples precisely, accurately, and efficiently. The latest member of the Roche cobas modular platform family, the cobas 8000 modular analyzer series allows compact and convenient consolidation of clinical chemistry and immunochemistry assays in high-workload laboratories with a throughput of 3 to 15 million tests annually. Here we present the results of studies designed to test the overall system performance under routine-like conditions that were conducted at 14 laboratories over 2 y. Experiments that test analytical performance of the new module were integrated with overall system functionality testing of all modules in different configurations. More than two million results were generated and evaluated for ~100 applications using serum/plasma, urine, or EDTA blood samples. During the workflow studies, eight configurations of the possible 38 combinations were used, covering all available analytical modules. The versatility of the module combinations makes the system customizable to fit the needs of diverse laboratories, allowing precise and accurate analysis of a broad spectrum of clinical chemistry and immunochemistry parameters with short turnaround times. This new system will contribute to the ability of clinical laboratories to offer better service to their customers and support vital clinical decision making.
KW - analytical modules
KW - analytical performance
KW - analyzers
KW - practicability assessment
KW - workflow analysis
UR - http://www.scopus.com/inward/record.url?scp=84887496376&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84887496376&partnerID=8YFLogxK
U2 - 10.1177/2211068212472183
DO - 10.1177/2211068212472183
M3 - Article
VL - 18
SP - 306
EP - 327
JO - JALA - Journal of the Association for Laboratory Automation
JF - JALA - Journal of the Association for Laboratory Automation
SN - 1535-5535
IS - 4
ER -