Abstract
Helicobacter pylori exists as an actively dividing spiral form and a nonculturable, but viable, metabolizing coccoid form. Both forms are present in the stomach, but their relative pathophysiologic significances are unknown. Here we show that the coccoid form of H. pylori, in contrast to the spiral form, binds poorly to gastric epithelial cells and induces little, if any, interleukin-8 secretion by these cells.
| Original language | English |
|---|---|
| Pages (from-to) | 843-846 |
| Number of pages | 4 |
| Journal | Infection and Immunity |
| Volume | 65 |
| Issue number | 2 |
| Publication status | Published - 1997 |
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ASJC Scopus subject areas
- Immunology
Cite this
Coccoid and spiral Helicobacter pylori differ in their abilities to adhere to gastric epithelial cells and induce interleukin-8 secretion. / Cole, S. P.; Cirillo, D.; Kagnoff, M. F.; Guiney, D. G.; Eckmann, L.
In: Infection and Immunity, Vol. 65, No. 2, 1997, p. 843-846.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Coccoid and spiral Helicobacter pylori differ in their abilities to adhere to gastric epithelial cells and induce interleukin-8 secretion
AU - Cole, S. P.
AU - Cirillo, D.
AU - Kagnoff, M. F.
AU - Guiney, D. G.
AU - Eckmann, L.
PY - 1997
Y1 - 1997
N2 - Helicobacter pylori exists as an actively dividing spiral form and a nonculturable, but viable, metabolizing coccoid form. Both forms are present in the stomach, but their relative pathophysiologic significances are unknown. Here we show that the coccoid form of H. pylori, in contrast to the spiral form, binds poorly to gastric epithelial cells and induces little, if any, interleukin-8 secretion by these cells.
AB - Helicobacter pylori exists as an actively dividing spiral form and a nonculturable, but viable, metabolizing coccoid form. Both forms are present in the stomach, but their relative pathophysiologic significances are unknown. Here we show that the coccoid form of H. pylori, in contrast to the spiral form, binds poorly to gastric epithelial cells and induces little, if any, interleukin-8 secretion by these cells.
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UR - http://www.scopus.com/inward/citedby.url?scp=0031027614&partnerID=8YFLogxK
M3 - Article
C2 - 9009355
AN - SCOPUS:0031027614
VL - 65
SP - 843
EP - 846
JO - Infection and Immunity
JF - Infection and Immunity
SN - 0019-9567
IS - 2
ER -