Coccoid and spiral Helicobacter pylori differ in their abilities to adhere to gastric epithelial cells and induce interleukin-8 secretion

S. P. Cole; D. Cirillo; M. F. Kagnoff; D. G. Guiney; L. Eckmann

Coccoid and spiral Helicobacter pylori differ in their abilities to adhere to gastric epithelial cells and induce interleukin-8 secretion

S. P. Cole, D. Cirillo, M. F. Kagnoff, D. G. Guiney, L. Eckmann

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Helicobacter pylori exists as an actively dividing spiral form and a nonculturable, but viable, metabolizing coccoid form. Both forms are present in the stomach, but their relative pathophysiologic significances are unknown. Here we show that the coccoid form of H. pylori, in contrast to the spiral form, binds poorly to gastric epithelial cells and induces little, if any, interleukin-8 secretion by these cells.

Original language	English
Pages (from-to)	843-846
Number of pages	4
Journal	Infection and Immunity
Volume	65
Issue number	2
Publication status	Published - 1997

ASJC Scopus subject areas

Immunology

Access to Document

Fingerprint Dive into the research topics of 'Coccoid and spiral Helicobacter pylori differ in their abilities to adhere to gastric epithelial cells and induce interleukin-8 secretion'. Together they form a unique fingerprint.

Cite this

@article{fb16cb30be54468e96567597a5260797,

title = "Coccoid and spiral Helicobacter pylori differ in their abilities to adhere to gastric epithelial cells and induce interleukin-8 secretion",

abstract = "Helicobacter pylori exists as an actively dividing spiral form and a nonculturable, but viable, metabolizing coccoid form. Both forms are present in the stomach, but their relative pathophysiologic significances are unknown. Here we show that the coccoid form of H. pylori, in contrast to the spiral form, binds poorly to gastric epithelial cells and induces little, if any, interleukin-8 secretion by these cells.",

author = "Cole, {S. P.} and D. Cirillo and Kagnoff, {M. F.} and Guiney, {D. G.} and L. Eckmann",

year = "1997",

language = "English",

volume = "65",

pages = "843--846",

journal = "Infection and Immunity",

issn = "0019-9567",

publisher = "American Society for Microbiology",

number = "2",

}

TY - JOUR

T1 - Coccoid and spiral Helicobacter pylori differ in their abilities to adhere to gastric epithelial cells and induce interleukin-8 secretion

AU - Cole, S. P.

AU - Cirillo, D.

AU - Kagnoff, M. F.

AU - Guiney, D. G.

AU - Eckmann, L.

PY - 1997

Y1 - 1997

N2 - Helicobacter pylori exists as an actively dividing spiral form and a nonculturable, but viable, metabolizing coccoid form. Both forms are present in the stomach, but their relative pathophysiologic significances are unknown. Here we show that the coccoid form of H. pylori, in contrast to the spiral form, binds poorly to gastric epithelial cells and induces little, if any, interleukin-8 secretion by these cells.

AB - Helicobacter pylori exists as an actively dividing spiral form and a nonculturable, but viable, metabolizing coccoid form. Both forms are present in the stomach, but their relative pathophysiologic significances are unknown. Here we show that the coccoid form of H. pylori, in contrast to the spiral form, binds poorly to gastric epithelial cells and induces little, if any, interleukin-8 secretion by these cells.

UR - http://www.scopus.com/inward/record.url?scp=0031027614&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031027614&partnerID=8YFLogxK

M3 - Article

C2 - 9009355

AN - SCOPUS:0031027614

VL - 65

SP - 843

EP - 846

JO - Infection and Immunity

JF - Infection and Immunity

SN - 0019-9567

IS - 2

ER -