Coexistence of Kaposi’s sarcoma and psoriasis

is there a hidden relationship?

Lucia Brambilla, Giovanni Genovese, Athanasia Tourlaki, Silvia Della Bella

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Background: The relationship between Kaposi’s sarcoma (KS) and psoriasis is still controversial. Objectives: To analyse the association between KS and psoriasis, address the hypothesis of a reciprocal influence between the two conditions relative to clinical presentation and evolution, and consider the best therapeutic approach to be used for the treatment of psoriasis in KS patients in order to avoid the typical induction or worsening of KS during immunosuppression. Materials & Methods: We retrospectively reviewed clinical records of 37 patients with KS and psoriasis. Fisher’s exact test was performed in order to compare epidemiological and clinical data between subsets of patients. Results: The prevalence of psoriasis in our KS population (n = 1407) was 2.6%. There were no statistically significant differences in terms of stage or rate of progression between KS patients with and without psoriasis, except for a higher frequency of patients with KS Stage IIB among patients with KS and psoriasis (p = 0.001). Conclusions: Patients with psoriasis have a risk of KS comparable to that of the general population. Psoriasis and KS do not appear to influence each other. For the treatment of psoriasis in KS patients, one should take into account the KS-inducing potential of certain anti-psoriatic drugs.

Original languageEnglish
Pages (from-to)320-325
Number of pages6
JournalEuropean Journal of Dermatology
Volume28
Issue number3
DOIs
Publication statusPublished - May 1 2018

Fingerprint

Kaposi's Sarcoma
Psoriasis
Immunosuppression
Population
Therapeutics

Keywords

  • Kaposi’s sarcoma
  • psoriasis
  • psoriatic arthritis

ASJC Scopus subject areas

  • Dermatology

Cite this

Coexistence of Kaposi’s sarcoma and psoriasis : is there a hidden relationship? / Brambilla, Lucia; Genovese, Giovanni; Tourlaki, Athanasia; Della Bella, Silvia.

In: European Journal of Dermatology, Vol. 28, No. 3, 01.05.2018, p. 320-325.

Research output: Contribution to journalReview article

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abstract = "Background: The relationship between Kaposi’s sarcoma (KS) and psoriasis is still controversial. Objectives: To analyse the association between KS and psoriasis, address the hypothesis of a reciprocal influence between the two conditions relative to clinical presentation and evolution, and consider the best therapeutic approach to be used for the treatment of psoriasis in KS patients in order to avoid the typical induction or worsening of KS during immunosuppression. Materials & Methods: We retrospectively reviewed clinical records of 37 patients with KS and psoriasis. Fisher’s exact test was performed in order to compare epidemiological and clinical data between subsets of patients. Results: The prevalence of psoriasis in our KS population (n = 1407) was 2.6{\%}. There were no statistically significant differences in terms of stage or rate of progression between KS patients with and without psoriasis, except for a higher frequency of patients with KS Stage IIB among patients with KS and psoriasis (p = 0.001). Conclusions: Patients with psoriasis have a risk of KS comparable to that of the general population. Psoriasis and KS do not appear to influence each other. For the treatment of psoriasis in KS patients, one should take into account the KS-inducing potential of certain anti-psoriatic drugs.",
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