TY - JOUR
T1 - Coexistence of migraine and cluster headache
T2 - Report of 10 cases and possible pathogenetic implications
AU - D'Amico, Domenico
AU - Centonze, Vincenzo
AU - Grazzi, Licia
AU - Leone, Massimo
AU - Ricchetti, Giuseppe
AU - Bussone, Gennaro
PY - 1997/1
Y1 - 1997/1
N2 - We report on 10 patients suffering from two types of primary headache, migraine and cluster, diagnosed according to (HS criteria, and selected from headache patients attending two Italian headache centers. We briefly review the literature on coexisting migraine and cluster headache, considering the time relationships between these two headaches. The present series seems not to confirm the hypothesis that migraine transforms into cluster headache since both headaches persist together in the patients. The series is of clinical interest particularly with regard to diagnosis end to treatment strategies. Furthermore, while migraine and cluster headache comorbidity must be confirmed by population-based epidemiological studies, the possibility arises that the two conditions may be linked pathophysiologically: common genetic factors or functional alterations in the same central neurological circuits may play a role in the pathogenesis of both disorders.
AB - We report on 10 patients suffering from two types of primary headache, migraine and cluster, diagnosed according to (HS criteria, and selected from headache patients attending two Italian headache centers. We briefly review the literature on coexisting migraine and cluster headache, considering the time relationships between these two headaches. The present series seems not to confirm the hypothesis that migraine transforms into cluster headache since both headaches persist together in the patients. The series is of clinical interest particularly with regard to diagnosis end to treatment strategies. Furthermore, while migraine and cluster headache comorbidity must be confirmed by population-based epidemiological studies, the possibility arises that the two conditions may be linked pathophysiologically: common genetic factors or functional alterations in the same central neurological circuits may play a role in the pathogenesis of both disorders.
KW - cluster headache
KW - comorbidity
KW - migraine
KW - pathophysiology
KW - time relationships
KW - treatment
UR - http://www.scopus.com/inward/record.url?scp=0031052865&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031052865&partnerID=8YFLogxK
U2 - 10.1046/j.1526-4610.1997.3701021.x
DO - 10.1046/j.1526-4610.1997.3701021.x
M3 - Article
C2 - 9046719
AN - SCOPUS:0031052865
VL - 37
SP - 21
EP - 25
JO - Headache
JF - Headache
SN - 0017-8748
IS - 1
ER -