Coexistence of TACS and trigeminal neuralgia: Pathophysiological conjectures

Massimo Leone, Eliana Mea, Sergio Genco, Gennaro Bussone

Research output: Contribution to journalArticle


Background. - Trigeminal autonomic cephalgias (TACs) and trigeminal neuralgia are short-lasting unilateral primary headaches whose study is providing insights into craniofacial pain mechanisms. We report on 2 patients in whom trigeminal neuralgia coexists with the TACs paroxysmal hemicrania and SUNCT. Conclusion. - Coexistence of trigeminal neuralgia with various TAC forms suggests a pathophysiological relationship between these short-lasting unilateral headaches.

Original languageEnglish
Pages (from-to)1565-1570
Number of pages6
Issue number10
Publication statusPublished - Nov 2006


  • Hypothalamus
  • Paroxysmal hemicrania
  • Pathophysiology
  • Trigeminal autonomic cephalgia
  • Trigeminal neuralgia

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

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