Coffee and tea drinking in relation to the risk of differentiated thyroid carcinoma: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Raul Zamora-Ros, Muath A. Alghamdi, Valerie Cayssials, Silvia Franceschi, Martin Almquist, Joakim Hennings, Maria Sandström, Konstantinos K. Tsilidis, Elisabete Weiderpass, Marie Christine Boutron-Ruault, Bodil Hammer Bech, Kim Overvad, Anne Tjønneland, Kristina E.N. Petersen, Francesca Romana Mancini, Yahya Mahamat-Saleh, Fabrice Bonnet, Tilman Kühn, Renée T. Fortner, Heiner BoeingAntonia Trichopoulou, Christina Bamia, Georgia Martimianaki, Giovanna Masala, Sara Grioni, Salvatore Panico, Rosario Tumino, Francesca Fasanelli, Guri Skeie, Tonje Braaten, Cristina Lasheras, Elena Salamanca-Fernández, Pilar Amiano, Maria Dolores Chirlaque, Aurelio Barricarte, Jonas Manjer, Peter Wallström, H. Bas Bueno-de-Mesquita, Petra H. Peeters, Kay Thee Khaw, Nicholas J. Wareham, Julie A. Schmidt, Dagfinn Aune, Graham Byrnes, Augustin Scalbert, Antonio Agudo, Sabina Rinaldi

Research output: Contribution to journalArticle

Abstract

Purpose: Coffee and tea constituents have shown several anti-carcinogenic activities in cellular and animal studies, including against thyroid cancer (TC). However, epidemiological evidence is still limited and inconsistent. Therefore, we aimed to investigate this association in a large prospective study. Methods: The study was conducted in the EPIC (European Prospective Investigation into Cancer and Nutrition) cohort, which included 476,108 adult men and women. Coffee and tea intakes were assessed through validated country-specific dietary questionnaires. Results: During a mean follow-up of 14 years, 748 first incident differentiated TC cases (including 601 papillary and 109 follicular TC) were identified. Coffee consumption (per 100 mL/day) was not associated either with total differentiated TC risk (HRcalibrated 1.00, 95% CI 0.97–1.04) or with the risk of TC subtypes. Tea consumption (per 100 mL/day) was not associated with the risk of total differentiated TC (HRcalibrated 0.98, 95% CI 0.95–1.02) and papillary tumor (HRcalibrated 0.99, 95% CI 0.95–1.03), whereas an inverse association was found with follicular tumor risk (HRcalibrated 0.90, 95% CI 0.81–0.99), but this association was based on a sub-analysis with a small number of cancer cases. Conclusions: In this large prospective study, coffee and tea consumptions were not associated with TC risk.

Original languageEnglish
JournalEuropean Journal of Nutrition
DOIs
Publication statusE-pub ahead of print - Jan 1 2018

Fingerprint

Coffee
Tea
Thyroid Neoplasms
Drinking
Neoplasms
Prospective Studies

Keywords

  • Coffee
  • Cohort
  • EPIC
  • Intake
  • Tea
  • Thyroid cancer

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Coffee and tea drinking in relation to the risk of differentiated thyroid carcinoma : results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. / Zamora-Ros, Raul; Alghamdi, Muath A.; Cayssials, Valerie; Franceschi, Silvia; Almquist, Martin; Hennings, Joakim; Sandström, Maria; Tsilidis, Konstantinos K.; Weiderpass, Elisabete; Boutron-Ruault, Marie Christine; Hammer Bech, Bodil; Overvad, Kim; Tjønneland, Anne; Petersen, Kristina E.N.; Mancini, Francesca Romana; Mahamat-Saleh, Yahya; Bonnet, Fabrice; Kühn, Tilman; Fortner, Renée T.; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; Martimianaki, Georgia; Masala, Giovanna; Grioni, Sara; Panico, Salvatore; Tumino, Rosario; Fasanelli, Francesca; Skeie, Guri; Braaten, Tonje; Lasheras, Cristina; Salamanca-Fernández, Elena; Amiano, Pilar; Chirlaque, Maria Dolores; Barricarte, Aurelio; Manjer, Jonas; Wallström, Peter; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Khaw, Kay Thee; Wareham, Nicholas J.; Schmidt, Julie A.; Aune, Dagfinn; Byrnes, Graham; Scalbert, Augustin; Agudo, Antonio; Rinaldi, Sabina.

In: European Journal of Nutrition, 01.01.2018.

Research output: Contribution to journalArticle

Zamora-Ros, R, Alghamdi, MA, Cayssials, V, Franceschi, S, Almquist, M, Hennings, J, Sandström, M, Tsilidis, KK, Weiderpass, E, Boutron-Ruault, MC, Hammer Bech, B, Overvad, K, Tjønneland, A, Petersen, KEN, Mancini, FR, Mahamat-Saleh, Y, Bonnet, F, Kühn, T, Fortner, RT, Boeing, H, Trichopoulou, A, Bamia, C, Martimianaki, G, Masala, G, Grioni, S, Panico, S, Tumino, R, Fasanelli, F, Skeie, G, Braaten, T, Lasheras, C, Salamanca-Fernández, E, Amiano, P, Chirlaque, MD, Barricarte, A, Manjer, J, Wallström, P, Bueno-de-Mesquita, HB, Peeters, PH, Khaw, KT, Wareham, NJ, Schmidt, JA, Aune, D, Byrnes, G, Scalbert, A, Agudo, A & Rinaldi, S 2018, 'Coffee and tea drinking in relation to the risk of differentiated thyroid carcinoma: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study', European Journal of Nutrition. https://doi.org/10.1007/s00394-018-1874-z
Zamora-Ros, Raul ; Alghamdi, Muath A. ; Cayssials, Valerie ; Franceschi, Silvia ; Almquist, Martin ; Hennings, Joakim ; Sandström, Maria ; Tsilidis, Konstantinos K. ; Weiderpass, Elisabete ; Boutron-Ruault, Marie Christine ; Hammer Bech, Bodil ; Overvad, Kim ; Tjønneland, Anne ; Petersen, Kristina E.N. ; Mancini, Francesca Romana ; Mahamat-Saleh, Yahya ; Bonnet, Fabrice ; Kühn, Tilman ; Fortner, Renée T. ; Boeing, Heiner ; Trichopoulou, Antonia ; Bamia, Christina ; Martimianaki, Georgia ; Masala, Giovanna ; Grioni, Sara ; Panico, Salvatore ; Tumino, Rosario ; Fasanelli, Francesca ; Skeie, Guri ; Braaten, Tonje ; Lasheras, Cristina ; Salamanca-Fernández, Elena ; Amiano, Pilar ; Chirlaque, Maria Dolores ; Barricarte, Aurelio ; Manjer, Jonas ; Wallström, Peter ; Bueno-de-Mesquita, H. Bas ; Peeters, Petra H. ; Khaw, Kay Thee ; Wareham, Nicholas J. ; Schmidt, Julie A. ; Aune, Dagfinn ; Byrnes, Graham ; Scalbert, Augustin ; Agudo, Antonio ; Rinaldi, Sabina. / Coffee and tea drinking in relation to the risk of differentiated thyroid carcinoma : results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. In: European Journal of Nutrition. 2018.
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title = "Coffee and tea drinking in relation to the risk of differentiated thyroid carcinoma: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study",
abstract = "Purpose: Coffee and tea constituents have shown several anti-carcinogenic activities in cellular and animal studies, including against thyroid cancer (TC). However, epidemiological evidence is still limited and inconsistent. Therefore, we aimed to investigate this association in a large prospective study. Methods: The study was conducted in the EPIC (European Prospective Investigation into Cancer and Nutrition) cohort, which included 476,108 adult men and women. Coffee and tea intakes were assessed through validated country-specific dietary questionnaires. Results: During a mean follow-up of 14 years, 748 first incident differentiated TC cases (including 601 papillary and 109 follicular TC) were identified. Coffee consumption (per 100 mL/day) was not associated either with total differentiated TC risk (HRcalibrated 1.00, 95{\%} CI 0.97–1.04) or with the risk of TC subtypes. Tea consumption (per 100 mL/day) was not associated with the risk of total differentiated TC (HRcalibrated 0.98, 95{\%} CI 0.95–1.02) and papillary tumor (HRcalibrated 0.99, 95{\%} CI 0.95–1.03), whereas an inverse association was found with follicular tumor risk (HRcalibrated 0.90, 95{\%} CI 0.81–0.99), but this association was based on a sub-analysis with a small number of cancer cases. Conclusions: In this large prospective study, coffee and tea consumptions were not associated with TC risk.",
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author = "Raul Zamora-Ros and Alghamdi, {Muath A.} and Valerie Cayssials and Silvia Franceschi and Martin Almquist and Joakim Hennings and Maria Sandstr{\"o}m and Tsilidis, {Konstantinos K.} and Elisabete Weiderpass and Boutron-Ruault, {Marie Christine} and {Hammer Bech}, Bodil and Kim Overvad and Anne Tj{\o}nneland and Petersen, {Kristina E.N.} and Mancini, {Francesca Romana} and Yahya Mahamat-Saleh and Fabrice Bonnet and Tilman K{\"u}hn and Fortner, {Ren{\'e}e T.} and Heiner Boeing and Antonia Trichopoulou and Christina Bamia and Georgia Martimianaki and Giovanna Masala and Sara Grioni and Salvatore Panico and Rosario Tumino and Francesca Fasanelli and Guri Skeie and Tonje Braaten and Cristina Lasheras and Elena Salamanca-Fern{\'a}ndez and Pilar Amiano and Chirlaque, {Maria Dolores} and Aurelio Barricarte and Jonas Manjer and Peter Wallstr{\"o}m and Bueno-de-Mesquita, {H. Bas} and Peeters, {Petra H.} and Khaw, {Kay Thee} and Wareham, {Nicholas J.} and Schmidt, {Julie A.} and Dagfinn Aune and Graham Byrnes and Augustin Scalbert and Antonio Agudo and Sabina Rinaldi",
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T1 - Coffee and tea drinking in relation to the risk of differentiated thyroid carcinoma

T2 - results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study

AU - Zamora-Ros, Raul

AU - Alghamdi, Muath A.

AU - Cayssials, Valerie

AU - Franceschi, Silvia

AU - Almquist, Martin

AU - Hennings, Joakim

AU - Sandström, Maria

AU - Tsilidis, Konstantinos K.

AU - Weiderpass, Elisabete

AU - Boutron-Ruault, Marie Christine

AU - Hammer Bech, Bodil

AU - Overvad, Kim

AU - Tjønneland, Anne

AU - Petersen, Kristina E.N.

AU - Mancini, Francesca Romana

AU - Mahamat-Saleh, Yahya

AU - Bonnet, Fabrice

AU - Kühn, Tilman

AU - Fortner, Renée T.

AU - Boeing, Heiner

AU - Trichopoulou, Antonia

AU - Bamia, Christina

AU - Martimianaki, Georgia

AU - Masala, Giovanna

AU - Grioni, Sara

AU - Panico, Salvatore

AU - Tumino, Rosario

AU - Fasanelli, Francesca

AU - Skeie, Guri

AU - Braaten, Tonje

AU - Lasheras, Cristina

AU - Salamanca-Fernández, Elena

AU - Amiano, Pilar

AU - Chirlaque, Maria Dolores

AU - Barricarte, Aurelio

AU - Manjer, Jonas

AU - Wallström, Peter

AU - Bueno-de-Mesquita, H. Bas

AU - Peeters, Petra H.

AU - Khaw, Kay Thee

AU - Wareham, Nicholas J.

AU - Schmidt, Julie A.

AU - Aune, Dagfinn

AU - Byrnes, Graham

AU - Scalbert, Augustin

AU - Agudo, Antonio

AU - Rinaldi, Sabina

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Purpose: Coffee and tea constituents have shown several anti-carcinogenic activities in cellular and animal studies, including against thyroid cancer (TC). However, epidemiological evidence is still limited and inconsistent. Therefore, we aimed to investigate this association in a large prospective study. Methods: The study was conducted in the EPIC (European Prospective Investigation into Cancer and Nutrition) cohort, which included 476,108 adult men and women. Coffee and tea intakes were assessed through validated country-specific dietary questionnaires. Results: During a mean follow-up of 14 years, 748 first incident differentiated TC cases (including 601 papillary and 109 follicular TC) were identified. Coffee consumption (per 100 mL/day) was not associated either with total differentiated TC risk (HRcalibrated 1.00, 95% CI 0.97–1.04) or with the risk of TC subtypes. Tea consumption (per 100 mL/day) was not associated with the risk of total differentiated TC (HRcalibrated 0.98, 95% CI 0.95–1.02) and papillary tumor (HRcalibrated 0.99, 95% CI 0.95–1.03), whereas an inverse association was found with follicular tumor risk (HRcalibrated 0.90, 95% CI 0.81–0.99), but this association was based on a sub-analysis with a small number of cancer cases. Conclusions: In this large prospective study, coffee and tea consumptions were not associated with TC risk.

AB - Purpose: Coffee and tea constituents have shown several anti-carcinogenic activities in cellular and animal studies, including against thyroid cancer (TC). However, epidemiological evidence is still limited and inconsistent. Therefore, we aimed to investigate this association in a large prospective study. Methods: The study was conducted in the EPIC (European Prospective Investigation into Cancer and Nutrition) cohort, which included 476,108 adult men and women. Coffee and tea intakes were assessed through validated country-specific dietary questionnaires. Results: During a mean follow-up of 14 years, 748 first incident differentiated TC cases (including 601 papillary and 109 follicular TC) were identified. Coffee consumption (per 100 mL/day) was not associated either with total differentiated TC risk (HRcalibrated 1.00, 95% CI 0.97–1.04) or with the risk of TC subtypes. Tea consumption (per 100 mL/day) was not associated with the risk of total differentiated TC (HRcalibrated 0.98, 95% CI 0.95–1.02) and papillary tumor (HRcalibrated 0.99, 95% CI 0.95–1.03), whereas an inverse association was found with follicular tumor risk (HRcalibrated 0.90, 95% CI 0.81–0.99), but this association was based on a sub-analysis with a small number of cancer cases. Conclusions: In this large prospective study, coffee and tea consumptions were not associated with TC risk.

KW - Coffee

KW - Cohort

KW - EPIC

KW - Intake

KW - Tea

KW - Thyroid cancer

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U2 - 10.1007/s00394-018-1874-z

DO - 10.1007/s00394-018-1874-z

M3 - Article

JO - European Journal of Nutrition

JF - European Journal of Nutrition

SN - 1436-6207

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