Coffee and tea intake and risk of brain tumors in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study

Dominique S. Michaud, Valentina Gallo, Brigitte Schlehofer, Anne Tjønneland, Anja Olsen, Kim Overvad, Christina C. Dahm, Birgit Teucher, Annekatrin Lukanova, Heiner Boeing, Madlen Schütze, Antonia Trichopoulou, Pagona Lagiou, Andreas Kyrozis, Carlotta Sacerdote, Vittorio Krogh, Giovanna Masala, Rosario Tumino, Amalia Mattiello, H. Bas Bueno-de-MesquitaMartine M. Ros, Petra H M Peeters, Carla H. Van Gils, Guri Skeie, Dagrun Engeset, Christine L. Parr, Eva Ardanaz, Maria Dolores Chirlaque, Miren Dorronsoro, Maria José Sánchez, Marcial Argüelles, Paula Jakszyn, Lena M. Nilsson, Beatrice S. Melin, Jonas Manjer, Elisabet Wirfält, Kay Tee Khaw, Nick Wareham, Naomi E. Allen, Timothy J. Key, Isabelle Romieu, Paolo Vineis, Elio Riboli

Research output: Contribution to journalArticle

Abstract

Background: In a recent US cohort study, total coffee and tea consumption was inversely associated with risk of glioma, and experimental studies showed that caffeine can slow the invasive growth of glioblastoma. Objective: The objective was to examine the relation between coffee and tea intake and the risk of glioma and meningioma in a large European cohort study, the European Prospective Investigation into Cancer and Nutrition (EPIC). Design: Data on coffee and tea intake were collected from men and women recruited into the EPIC cohort study. Over an average of 8.5 y of follow-up, 343 cases of glioma and 245 cases of meningioma were newly diagnosed in 9 countries. We used Cox proportional hazards models to examine the relation between coffee and tea and brain tumors. Results: We observed no associations between coffee, tea, or combined coffee and tea consumption and risk of either type of brain tumor when using quantiles based on country-specific distributions of intake. However, a significant inverse association was observed for glioma risk among those consuming ≥100 mL coffee and tea per day compared with those consuming

Original languageEnglish
Pages (from-to)1145-1150
Number of pages6
JournalAmerican Journal of Clinical Nutrition
Volume92
Issue number5
DOIs
Publication statusPublished - Nov 1 2010

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Medicine(all)

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    Michaud, D. S., Gallo, V., Schlehofer, B., Tjønneland, A., Olsen, A., Overvad, K., Dahm, C. C., Teucher, B., Lukanova, A., Boeing, H., Schütze, M., Trichopoulou, A., Lagiou, P., Kyrozis, A., Sacerdote, C., Krogh, V., Masala, G., Tumino, R., Mattiello, A., ... Riboli, E. (2010). Coffee and tea intake and risk of brain tumors in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study. American Journal of Clinical Nutrition, 92(5), 1145-1150. https://doi.org/10.3945/ajcn.2010.29876