Coffee drinking and risk of preterm birth

F. Chiaffarino, F. Parazzini, L. Chatenoud, E. Ricci, L. Tozzi, V. Chiantera, C. Maffioletti, L. Fedele

Research output: Contribution to journalArticlepeer-review


Objectives: We analysed the association between coffee drinking before and during the three trimesters of pregnancy and the risk of preterm birth of babies normal for gestational age (NGA) or small for gestational age (SGA). Methods: Case-control study conducted in University clinics of North Italy. Cases were 502 women who delivered at <weeks of gestation. The controls included 1966 women who gave birth at term (≥37 weeks of gestation) to healthy infants on randomly selected days at the hospitals where cases had been identified. Results: There was inverse association for coffee consumption in the third trimester of pregnancy in SGA cases compared to NGA (heterogeneity test between OR: χ12 P≤0.05). In comparison with not drinkers, all the ORs of overall intake of caffeine were closed near the unity for both SGA and NGA preterm birth. Conclusion: Compared with no consumption, a low consumption of coffee during pregnancy may not have significant effects on preterm birth.

Original languageEnglish
Pages (from-to)610-613
Number of pages4
JournalEuropean Journal of Clinical Nutrition
Issue number5
Publication statusPublished - May 2006


  • Coffee
  • Epidemiology
  • Normal for gestational age
  • Preterm birth
  • Risk factors
  • Small for gestational age

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science


Dive into the research topics of 'Coffee drinking and risk of preterm birth'. Together they form a unique fingerprint.

Cite this