Cognitive effects of valproate

Roberto Gallassi, Angela Morreale, Sebastiano Lorusso, Gaetano Procaccianti, Elio Lugaresi, Agostino Baruzzi

Research output: Contribution to journalArticle


The effects of valproate on cognition are usually considered to be minimal, but few formal neuropsychological studies are available. We studied the psychomotor performances of 20 seizure-free epileptics during fixed valproate monotherapy and after its withdrawal. Our findings suggest some adverse effects of valproate which appear to be completely reversible after withdrawal.

Original languageEnglish
Pages (from-to)160-164
Number of pages5
JournalEpilepsy Research
Issue number2
Publication statusPublished - 1990



  • Anticonvulsants
  • Epilepsy
  • Neuropsychological tests
  • Valproate

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neurology

Cite this

Gallassi, R., Morreale, A., Lorusso, S., Procaccianti, G., Lugaresi, E., & Baruzzi, A. (1990). Cognitive effects of valproate. Epilepsy Research, 5(2), 160-164.