Cognitive evoked potentials in obstructive sleep apnea syndrome: A review of the literature

Alberto Raggi, Raffaele Ferri

Research output: Contribution to journalArticle

Abstract

Cognitive functions may be altered in patients with obstructive sleep apnea syndrome (OSAS) and it has been proposed that vigilance and attention changes play a fundamental role in all aspects of cognitive defi cits noted in this disease. The use of event-related potentials (ERPs) is a high-time resolution technique that can be used to explore the presence of cognitive dysfunction. We review 23 empirical articles on ERPs in OSAS in order to contribute to the clarifi cation of the pattern of cognitive defi cits that are specifi c to this disease and to see whether there might be an improvement of abnormal psychophysiological fi ndings with continuous positive airway pressure (CPAP) treatment. We conclude that ERP studies have contributed to demonstrating changes in cognitive attentive processing in OSAS, mainly in association with altered functioning of the prefrontal cortex, and that CPAP treatment may improve vigilance and attention and generally improve cerebral information processing in these patients. The remaining defi cits during suffi cient CPAP therapy may, however, refl ect irreversible hypoxic cerebral damage.

Original languageEnglish
Pages (from-to)311-323
Number of pages13
JournalReviews in the Neurosciences
Volume23
Issue number3
DOIs
Publication statusPublished - Jun 2012

Fingerprint

Continuous Positive Airway Pressure
Obstructive Sleep Apnea
Evoked Potentials
Prefrontal Cortex
Automatic Data Processing
Cognition
Cations
Therapeutics

Keywords

  • Attention
  • Cognitive defi cit
  • Continuous positive airway pressure treatment
  • Event-related potentials
  • Information processing
  • Obstructive sleep apnea syndrome.

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Cognitive evoked potentials in obstructive sleep apnea syndrome : A review of the literature. / Raggi, Alberto; Ferri, Raffaele.

In: Reviews in the Neurosciences, Vol. 23, No. 3, 06.2012, p. 311-323.

Research output: Contribution to journalArticle

@article{1482cd0c840e424baf69bdf8c9df2576,
title = "Cognitive evoked potentials in obstructive sleep apnea syndrome: A review of the literature",
abstract = "Cognitive functions may be altered in patients with obstructive sleep apnea syndrome (OSAS) and it has been proposed that vigilance and attention changes play a fundamental role in all aspects of cognitive defi cits noted in this disease. The use of event-related potentials (ERPs) is a high-time resolution technique that can be used to explore the presence of cognitive dysfunction. We review 23 empirical articles on ERPs in OSAS in order to contribute to the clarifi cation of the pattern of cognitive defi cits that are specifi c to this disease and to see whether there might be an improvement of abnormal psychophysiological fi ndings with continuous positive airway pressure (CPAP) treatment. We conclude that ERP studies have contributed to demonstrating changes in cognitive attentive processing in OSAS, mainly in association with altered functioning of the prefrontal cortex, and that CPAP treatment may improve vigilance and attention and generally improve cerebral information processing in these patients. The remaining defi cits during suffi cient CPAP therapy may, however, refl ect irreversible hypoxic cerebral damage.",
keywords = "Attention, Cognitive defi cit, Continuous positive airway pressure treatment, Event-related potentials, Information processing, Obstructive sleep apnea syndrome.",
author = "Alberto Raggi and Raffaele Ferri",
year = "2012",
month = "6",
doi = "10.1515/revneuro-2012-0027",
language = "English",
volume = "23",
pages = "311--323",
journal = "Reviews in the Neurosciences",
issn = "0334-1763",
publisher = "Walter de Gruyter GmbH & Co. KG",
number = "3",

}

TY - JOUR

T1 - Cognitive evoked potentials in obstructive sleep apnea syndrome

T2 - A review of the literature

AU - Raggi, Alberto

AU - Ferri, Raffaele

PY - 2012/6

Y1 - 2012/6

N2 - Cognitive functions may be altered in patients with obstructive sleep apnea syndrome (OSAS) and it has been proposed that vigilance and attention changes play a fundamental role in all aspects of cognitive defi cits noted in this disease. The use of event-related potentials (ERPs) is a high-time resolution technique that can be used to explore the presence of cognitive dysfunction. We review 23 empirical articles on ERPs in OSAS in order to contribute to the clarifi cation of the pattern of cognitive defi cits that are specifi c to this disease and to see whether there might be an improvement of abnormal psychophysiological fi ndings with continuous positive airway pressure (CPAP) treatment. We conclude that ERP studies have contributed to demonstrating changes in cognitive attentive processing in OSAS, mainly in association with altered functioning of the prefrontal cortex, and that CPAP treatment may improve vigilance and attention and generally improve cerebral information processing in these patients. The remaining defi cits during suffi cient CPAP therapy may, however, refl ect irreversible hypoxic cerebral damage.

AB - Cognitive functions may be altered in patients with obstructive sleep apnea syndrome (OSAS) and it has been proposed that vigilance and attention changes play a fundamental role in all aspects of cognitive defi cits noted in this disease. The use of event-related potentials (ERPs) is a high-time resolution technique that can be used to explore the presence of cognitive dysfunction. We review 23 empirical articles on ERPs in OSAS in order to contribute to the clarifi cation of the pattern of cognitive defi cits that are specifi c to this disease and to see whether there might be an improvement of abnormal psychophysiological fi ndings with continuous positive airway pressure (CPAP) treatment. We conclude that ERP studies have contributed to demonstrating changes in cognitive attentive processing in OSAS, mainly in association with altered functioning of the prefrontal cortex, and that CPAP treatment may improve vigilance and attention and generally improve cerebral information processing in these patients. The remaining defi cits during suffi cient CPAP therapy may, however, refl ect irreversible hypoxic cerebral damage.

KW - Attention

KW - Cognitive defi cit

KW - Continuous positive airway pressure treatment

KW - Event-related potentials

KW - Information processing

KW - Obstructive sleep apnea syndrome.

UR - http://www.scopus.com/inward/record.url?scp=84867284938&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84867284938&partnerID=8YFLogxK

U2 - 10.1515/revneuro-2012-0027

DO - 10.1515/revneuro-2012-0027

M3 - Article

C2 - 22752788

AN - SCOPUS:84867284938

VL - 23

SP - 311

EP - 323

JO - Reviews in the Neurosciences

JF - Reviews in the Neurosciences

SN - 0334-1763

IS - 3

ER -