ANALISI DELLA COERENZA NELLA MALATTIA DI ALZHEIMER

Translated title of the contribution: Coherence analysis in Alzheimer's disease

G. Comi, T. Locatelli, M. Cursi, M. Mauri, A. Elia, D. Liberati

Research output: Contribution to journalArticle

Abstract

The analysis of EEG coherence allows to study coupling of bioelectrical activity of different cerebral areas and gives informations about inter and intra-hemispheric connections. EEG coherence, at rest, has been evaluated with an AutoRegressive parametric model in 10 patients affected by probable Alzheimer's Disease. Six patients presented a decreased alpha band coherence, more prounounced over temporo-parietal region in 3 patients and in frontal region in other 2 patients. In 2 out of these 6 patients, there was a significant increase of delta coherence, without phase shift, more pronounced over regions far from the examined electrode. These two changes are probably related to different pathophysiologic events: alpha coherence decrease is due to alterations of cortico-cortical connections while delta coherence increase is secondary to the involvement of cholinergic pathways projecting diffusely to cortical areas.

Translated title of the contributionCoherence analysis in Alzheimer's disease
Original languageItalian
Pages (from-to)505-508
Number of pages4
JournalRivista di Neurobiologia
Volume40
Issue number5-6
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Neuroscience(all)

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    Comi, G., Locatelli, T., Cursi, M., Mauri, M., Elia, A., & Liberati, D. (1994). ANALISI DELLA COERENZA NELLA MALATTIA DI ALZHEIMER. Rivista di Neurobiologia, 40(5-6), 505-508.