Colloidal gold sulphide in the therapy of rheumatoid arthritis: Report of 320 cases

F. Zizzi, A. Ferruzzi, L. Frizziero

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Colloidal gold preparations are less used than other gold compounds in R.A. therapy because of their doubtful efficacy. We have studied the effects of intravenously administered colloidal gold sulphide 2% on 320 patients affected with classical and definite R.A. The initial doses were 17 mg, 51 mg and 87 mg at three to five day intervals, followed by 87 mg once a week until a total dose of 1000 mg was reached. If gold proved effective the dose frequency was gradually reduced to once in four weeks. We stopped chrysotherapy only if still ineffective after 6 months or if side-effects had appeared. Our clinical experience is in agreement with the results obtained in more recent controlled trials. We observed a more frequent therapeutic effect (69%) in the early stages of disease (12 months or less) and a definite reduction in titres of rheumatoid factor.

Original languageEnglish
Pages (from-to)9-14
Number of pages6
JournalRhumatologie - Revue International de Rhumatologie
Issue number1 NO. 76
Publication statusPublished - 1985

ASJC Scopus subject areas

  • Rheumatology


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