Colobronchial fistula: An unusual complication after peritonectomy and hyperthermic intra-peritoneal chemotherapy (HIPEC)

Barbara Laterza, Dario Baratti, Guido Cozzi, Shigeki Kusamura, Grazia Daniela Oliva, Cecilia Gavazzi, Luca Fumagalli, Alessandro Sironi, Domenico Sabia, Marcello Deraco

Research output: Contribution to journalArticle

Abstract

Background: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is an innovative approach to peritoneal carcinomatosis. Due to the complexity of the combined procedure, high rates of potentially life-threatening complications have been reported. This is the first report of colobronchial fistula following CRS and HIPEC. Case Report: A 70-year-old woman underwent CRS and HIPEC for papillary well-differentiated peritoneal mesothelioma. During the postoperative course, recurrent pneumonia occurred and bacteria of intestinal origin were isolated from expectorated sputum. Water-soluble contrast studies revealed direct communication between the left colon flexure and the bronchial tree. After appropriate medical and supportive therapies, the patient underwent resection of the splenic flexure and immediate anastomosis with complete recovery. Conclusion: Colobronchial fistula is a rare and potentially lethal complication of CRS and HIPEC. A suggestive clinical picture and contrast studies allow conclusive diagnosis to be made. Surgery is a safe and effective therapeutic option.

Original languageEnglish
Pages (from-to)151-154
Number of pages4
JournalIn Vivo
Volume23
Issue number1
Publication statusPublished - Jan 2009

Keywords

  • Colobronchial fistula
  • Intraperitioneal hyperthermic perfusion
  • Locoregional chemotherapy
  • Peritonectomy

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology

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    Laterza, B., Baratti, D., Cozzi, G., Kusamura, S., Oliva, G. D., Gavazzi, C., Fumagalli, L., Sironi, A., Sabia, D., & Deraco, M. (2009). Colobronchial fistula: An unusual complication after peritonectomy and hyperthermic intra-peritoneal chemotherapy (HIPEC). In Vivo, 23(1), 151-154.