TY - JOUR
T1 - Colon cancer
AU - Labianca, Roberto
AU - Beretta, Giordano D.
AU - Kildani, Basem
AU - Milesi, Laura
AU - Merlin, Federica
AU - Mosconi, Stefania
AU - Pessi, M. Adelaide
AU - Prochilo, Tiziana
AU - Quadri, Antonello
AU - Gatta, Gemma
AU - de Braud, Filippo
AU - Wils, Jacques
PY - 2010/5
Y1 - 2010/5
N2 - Colon cancer is one of the leading tumours in the world and it is considered among the big killers, together with lung, prostate and breast cancer. In the recent years very important advances occurred in the field of treatment of this frequent disease: adjuvant chemotherapy was demonstrated to be effective, chiefly in stage III patients, and surgery was optimized in order to achieve the best results with a low morbidity. Several new target-oriented drugs are under evaluation and some of them (cetuximab and bevacizumab) have already exhibited a good activity/efficacy, mainly in combination with chemotherapy. The development of updated recommendations for the best management of these patients is crucial in order to obtain the best results, not only in clinical research but also in every-day practice. This report summarizes the most important achievements in this field and provides the readers useful suggestions for their professional practice.
AB - Colon cancer is one of the leading tumours in the world and it is considered among the big killers, together with lung, prostate and breast cancer. In the recent years very important advances occurred in the field of treatment of this frequent disease: adjuvant chemotherapy was demonstrated to be effective, chiefly in stage III patients, and surgery was optimized in order to achieve the best results with a low morbidity. Several new target-oriented drugs are under evaluation and some of them (cetuximab and bevacizumab) have already exhibited a good activity/efficacy, mainly in combination with chemotherapy. The development of updated recommendations for the best management of these patients is crucial in order to obtain the best results, not only in clinical research but also in every-day practice. This report summarizes the most important achievements in this field and provides the readers useful suggestions for their professional practice.
KW - Colon cancer
KW - Strategy
KW - Treatment
UR - http://www.scopus.com/inward/record.url?scp=77950085360&partnerID=8YFLogxK
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U2 - 10.1016/j.critrevonc.2010.01.010
DO - 10.1016/j.critrevonc.2010.01.010
M3 - Article
C2 - 20138539
AN - SCOPUS:77950085360
VL - 74
SP - 106
EP - 133
JO - Critical Reviews in Oncology/Hematology
JF - Critical Reviews in Oncology/Hematology
SN - 1040-8428
IS - 2
ER -