Abstract
AIM: To evaluate whether FDG-positron emission tomography (PET)/computed tomography (CT) may be an accurate technique in the assessment of the T stage in patients with colorectal cancer. METHODS: Thirty four consecutive patients (20 men and 14 women; mean age: 63 years) with a histologically proven diagnosis of colorectal adenocarcinoma and scheduled for surgery in our hospital were enrolled in this study. All patients underwent FDG-PET/CT preoperatively. The primary tumor site and extent were evaluated on PET/CT images. Colorectal wall invasion was analysed according to a modified T classification that considers only three stages (≤ T2, T3, T4). Assessment of accuracy was carried out using 95% confidence intervals for T. RESULTS: Thirty five/37 (94.6%) adenocarcinomas were identified and correctly located on PET/CT images. PET/CT correctly staged the T of 33/35 lesions identified showing an accuracy of 94.3% (95% CI: 87%-100%). All T1, T3 and T4 lesions were correctly staged, while two T2 neoplasms were overstated as T3. CONCLUSION: Our data suggest that FDG-PET/CT may be an accurate modality for identifying primary tumor and defining its local extent in patients with colorectal cancer.
| Original language | English |
|---|---|
| Pages (from-to) | 1427-1433 |
| Number of pages | 7 |
| Journal | World Journal of Gastroenterology |
| Volume | 17 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - Mar 21 2011 |
Fingerprint
Keywords
- Cancer
- Colorectal
- Positron emission tomography/computed tomography
- Staging
ASJC Scopus subject areas
- Gastroenterology
Cite this
Colorectal cancer and 18FDG-PET/CT : What about adding the T to the N parameter in loco-regional staging? / Mainenti, Pier Paolo; Iodice, Delfina; Segreto, Sabrina; Storto, Giovanni; Magliulo, Mario; De Palma, Giovanni D.; Salvatore, Marco; Pace, Leonardo.
In: World Journal of Gastroenterology, Vol. 17, No. 11, 21.03.2011, p. 1427-1433.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Colorectal cancer and 18FDG-PET/CT
T2 - What about adding the T to the N parameter in loco-regional staging?
AU - Mainenti, Pier Paolo
AU - Iodice, Delfina
AU - Segreto, Sabrina
AU - Storto, Giovanni
AU - Magliulo, Mario
AU - De Palma, Giovanni D.
AU - Salvatore, Marco
AU - Pace, Leonardo
PY - 2011/3/21
Y1 - 2011/3/21
N2 - AIM: To evaluate whether FDG-positron emission tomography (PET)/computed tomography (CT) may be an accurate technique in the assessment of the T stage in patients with colorectal cancer. METHODS: Thirty four consecutive patients (20 men and 14 women; mean age: 63 years) with a histologically proven diagnosis of colorectal adenocarcinoma and scheduled for surgery in our hospital were enrolled in this study. All patients underwent FDG-PET/CT preoperatively. The primary tumor site and extent were evaluated on PET/CT images. Colorectal wall invasion was analysed according to a modified T classification that considers only three stages (≤ T2, T3, T4). Assessment of accuracy was carried out using 95% confidence intervals for T. RESULTS: Thirty five/37 (94.6%) adenocarcinomas were identified and correctly located on PET/CT images. PET/CT correctly staged the T of 33/35 lesions identified showing an accuracy of 94.3% (95% CI: 87%-100%). All T1, T3 and T4 lesions were correctly staged, while two T2 neoplasms were overstated as T3. CONCLUSION: Our data suggest that FDG-PET/CT may be an accurate modality for identifying primary tumor and defining its local extent in patients with colorectal cancer.
AB - AIM: To evaluate whether FDG-positron emission tomography (PET)/computed tomography (CT) may be an accurate technique in the assessment of the T stage in patients with colorectal cancer. METHODS: Thirty four consecutive patients (20 men and 14 women; mean age: 63 years) with a histologically proven diagnosis of colorectal adenocarcinoma and scheduled for surgery in our hospital were enrolled in this study. All patients underwent FDG-PET/CT preoperatively. The primary tumor site and extent were evaluated on PET/CT images. Colorectal wall invasion was analysed according to a modified T classification that considers only three stages (≤ T2, T3, T4). Assessment of accuracy was carried out using 95% confidence intervals for T. RESULTS: Thirty five/37 (94.6%) adenocarcinomas were identified and correctly located on PET/CT images. PET/CT correctly staged the T of 33/35 lesions identified showing an accuracy of 94.3% (95% CI: 87%-100%). All T1, T3 and T4 lesions were correctly staged, while two T2 neoplasms were overstated as T3. CONCLUSION: Our data suggest that FDG-PET/CT may be an accurate modality for identifying primary tumor and defining its local extent in patients with colorectal cancer.
KW - Cancer
KW - Colorectal
KW - Positron emission tomography/computed tomography
KW - Staging
UR - http://www.scopus.com/inward/record.url?scp=79955941400&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79955941400&partnerID=8YFLogxK
U2 - 10.3748/wjg.v17.i11.1427
DO - 10.3748/wjg.v17.i11.1427
M3 - Article
VL - 17
SP - 1427
EP - 1433
JO - World Journal of Gastroenterology
JF - World Journal of Gastroenterology
SN - 1007-9327
IS - 11
ER -