Ulcerative colitis predisposes to colorectal cancer: the risk increases along with disease duration and extension. Also some subsets of patients are at increased risk, namely patients with early onset of colitis, and patients with primary sclerosing cholangitis. Cancer complicating ulcerative colitis affects evenly all the colon, and is not located more frequently in the rectum and in the sigmoid colon, as well as the sporadic counterpart. Multiple cancers and cancers associated with high grade dysplasia are not infrequent in ulcerative colitis; for this reason, and for controlling the colitis, the treatment of choice is total colectomy, with or without colostomy. The prognosis of cancer complicating ulcerative colitis is similar to the sporadic counterpart. The Authors present a colon cancers series as a complication of coliris occurred at Regina Elena Cancer Institute of Rome, Italy, over the period 1975-1998.
|Number of pages||4|
|Journal||Journal of Experimental and Clinical Cancer Research|
|Publication status||Published - Mar 1999|
- Colon cancer
- Ulcerative colitis
ASJC Scopus subject areas
- Cancer Research