Colorectal cancer: Prognostic and predictive response therapy factors

M. Berretta, G. Nasti, V. Canzonieri, M. Di Vita, U. Tirelli, C. De Divitiis

Research output: Chapter in Book/Report/Conference proceedingChapter


Colorectal cancer (CRC) is the third most common cancer worldwide. Its prognosis is closely related to the stage of the disease at the time of diagnosis. This is a review on the role of pathological classical factors, serum/clinical biomarkers and characteristics with prognostic and predictive response therapy value in the management of CRC. Clinical follow-up in CRC is of paramount importance in the correct approach to this disease. Moreover, molecular studies have recently widened the opportunity for testing new possible markers, but actually, only few markers can be recommended for practical use in clinic. In the next future the hope will be to have a complete panel of clinical biomarkers to use in every setting of CRC disease, and at the same time to receive information about prognostic significance by their expression and to be oriented in the choice of the adequate treatment.

Original languageEnglish
Title of host publicationPrognostic and Predictive Response Therapy Factors in Cancer Disease (Colorectal, Breast, Liver, Lung, Gastric, Renal and Prostate Cancers)
PublisherNova Science Publishers, Inc.
Number of pages27
ISBN (Print)9781634635530, 9781634635455
Publication statusPublished - Jan 1 2015

ASJC Scopus subject areas

  • Medicine(all)


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