Abstract
Colorectal cancer (CRC) is a major health problem in western countries. It is the most frequently diagnosed cancer in EU countries with about 220 000 new cases per year; the number of CRC deaths approaches 112 000. Most cancer arises from adenomatous polyps through the adenoma-carcinoma sequence; the natural history of the disease is long: the risk of invasive cancer in adenoma is about 2% per year. Given the natural history of CRC, early diagnosis represents the most appropriate tool to reduce the disease-related mortality. Several tests are available to screen healthy subjects at average risk for CRC: faecal occult blood tests, flexible sigmoidoscopy, combined faecal occult blood tests and flexible sigmoidoscopy, total colonoscopy and double contrast barium enema. Issues related to the introduction on a large scale of population-based screening programmes for CRC are discussed.
Original language | English |
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Journal | Techniques in Coloproctology |
Volume | 8 |
Issue number | SUPPL. 2 |
DOIs | |
Publication status | Published - Dec 2004 |
Keywords
- Colonoscopy
- Colorectal cancer screening
- Evidence of benefits
- Faecal occult blood tests
- Sigmoidoscopy
ASJC Scopus subject areas
- Gastroenterology
- Surgery