Combination of variant and microvascular angina

Fabio Infusino, Gaetano A. Lanza, Alfonso Sestito, Gregory A. Sgueglia, Filippo Crea, Attilio Maseri

Research output: Contribution to journalArticlepeer-review


Prinzmetal's variant angina (VA) and cardiac syndrome X (CSX) are two distinct, usually easily recognizable, forms of angina syndromes, caused by epicardial spasm, usually responsible for transient transmural myocardial ischemia at rest and by coronary microvascular dysfunction (CMVD), usually responsible for effort induced subendocardial ischemia, respectively. In this article we report clinical evidence in three patients of the simultaneous occurrence of angina episodes typical of both VA and CSX, suggesting that common pathogenetic factors may be responsible for clinical manifestations both of functional macrovascular and microvascular coronary artery abnormalities in some angina patients.

Original languageEnglish
JournalClinical Cardiology
Issue number8
Publication statusPublished - Aug 2009

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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