Combined approach for spontaneous rupture of hepatocellular carcinoma

Anna Rossetto, Gian Luigi Adani, Andrea Risaliti, Umberto Baccarani, Vittorio Bresadola, Dario Lorenzin, Giovanni Terrosu

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Ruptured hepatocellular carcinoma is a rare, emergency occurrence in western countries with high mortality risk. A number of hypotheses have been formulated in order to explain the precise mechanism that leads to hepatocellular carcinoma (HCC) rupture: sub-capsular location, dimensions, portal hypertension, tumour necrosis, local increase of venous pressure due to the outflow reduction caused by neoplastic invasion, and the presence of a previous vascular injury which might predispose to HCC rupture. There is still a debate in the literature concerning the best approach in cases of HCC rupture. Surgery is the first option for treatment of acute abdominal bleeding. However the advent of endovascular treatments widens the range of possible therapies for acute bleeding control and subsequent ablation purposes. We report a case of hemoperitoneum from spontaneous rupture of undiagnosed HCC, that was treated successfully by emergency surgical resection followed by transarterial chemo-embolization for local recurrence.

Original languageEnglish
Pages (from-to)49-51
Number of pages3
JournalWorld Journal of Hepatology
Volume2
Issue number1
DOIs
Publication statusPublished - 2010

Fingerprint

Spontaneous Rupture
Hepatocellular Carcinoma
Rupture
Emergencies
Hemorrhage
Hemoperitoneum
Venous Pressure
Vascular System Injuries
Portal Hypertension
Necrosis
Recurrence
Mortality
Neoplasms

Keywords

  • Acute abdominal bleeding
  • Bleeding hepatocellular carcinoma
  • Hemoperitoneum

ASJC Scopus subject areas

  • Hepatology

Cite this

Rossetto, A., Adani, G. L., Risaliti, A., Baccarani, U., Bresadola, V., Lorenzin, D., & Terrosu, G. (2010). Combined approach for spontaneous rupture of hepatocellular carcinoma. World Journal of Hepatology, 2(1), 49-51. https://doi.org/10.4254/wjh.v2.i1.49

Combined approach for spontaneous rupture of hepatocellular carcinoma. / Rossetto, Anna; Adani, Gian Luigi; Risaliti, Andrea; Baccarani, Umberto; Bresadola, Vittorio; Lorenzin, Dario; Terrosu, Giovanni.

In: World Journal of Hepatology, Vol. 2, No. 1, 2010, p. 49-51.

Research output: Contribution to journalArticle

Rossetto, A, Adani, GL, Risaliti, A, Baccarani, U, Bresadola, V, Lorenzin, D & Terrosu, G 2010, 'Combined approach for spontaneous rupture of hepatocellular carcinoma', World Journal of Hepatology, vol. 2, no. 1, pp. 49-51. https://doi.org/10.4254/wjh.v2.i1.49
Rossetto A, Adani GL, Risaliti A, Baccarani U, Bresadola V, Lorenzin D et al. Combined approach for spontaneous rupture of hepatocellular carcinoma. World Journal of Hepatology. 2010;2(1):49-51. https://doi.org/10.4254/wjh.v2.i1.49
Rossetto, Anna ; Adani, Gian Luigi ; Risaliti, Andrea ; Baccarani, Umberto ; Bresadola, Vittorio ; Lorenzin, Dario ; Terrosu, Giovanni. / Combined approach for spontaneous rupture of hepatocellular carcinoma. In: World Journal of Hepatology. 2010 ; Vol. 2, No. 1. pp. 49-51.
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