Combined central and peripheral acute demyelination

D. Pareyson, C. Ciano, F. Fiacchino, M. Gemma, M. Savoiardo, A. Sghirlanzoni

Research output: Contribution to journalArticlepeer-review


We describe a patient with multiple sclerosis who had a bout of central demyelination associated with an acute inflammatory demyelinating polyneuropathy. The contemporary involvement of central and peripheral nervous system due to a demyelinating disease has been reported anecdotically in humans, and can be induced experimentally in animals. It may be sustained by a common pathogenetic factor.

Original languageEnglish
Pages (from-to)83-86
Number of pages4
JournalItalian Journal of Neurological Sciences
Issue number1
Publication statusPublished - Feb 1993


  • demyelinating diseases
  • multiple sclerosis
  • myelin sheath
  • peripheral neuropathy
  • Polyradiculoneuritis

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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