Combined craniofacial approach to facial tumours involving the anterior skull base

G. Margarino, M. Scala, P. Mereu, D. Comandini, G. Schenone, A. Galli, N. Francaviglia, M. Gipponi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The authors report their experience on six male patients and one female patient (age range: 58-76 years, median: 67) with facial tumours involving the anterior skull base, undergoing craniofacial resection between January 1992 and May 1994 at the Division of Surgical Oncology in the Tumor Institute, Genoa. Three patients had squamous carcinoma and adenocarcinoma of the nasal fossa; two patients had squamous carcinoma rT4NO and adenocarcinoma rT4NO1 of the maxillary sinus; one patient had squamous carcinoma of the eyelid, and another had squamous carcinoma of the internal chantus. Four patients had had previous radiotherapy, another underwent pre-operative chemoradiotherapy, and only two patients had not been treated before. A proper craniofacial tumour resection was performed in three patients; one patient had a left maxillectomy with ethmoidectomy and orbital exenteration; one patient underwent maxillectomy, resection of the medial and inferior wall of the orbit, ethmoidectomy, and orbital exenteration; one patient underwent maxillectomy, ethmoidectomy, and mucosectomy of the sphenoidal sinus, and one patient had total ethmoidectomy. As for reconstruction procedures of the anterior skull base, lyophilized dura with galeal pericranial flap was commonly used. A myocutaneous flap transposition (transverse rectus abdominis and latissimus dorsi myocutaneous flap) was used in two patients for the reconstruction of the resected tissues and bones of maxillary and orbital regions. Post-operative complications included intraoperative liquorrhea in one patient; one case of early and serious pneumocephalus; flap necrosis occurred following transposition of latissimus dorsi. Median hospital stay was 34 days. After a median follow-up of 18 months (range: 3 to 34 months) five of seven patients (71.4%) are alive and disease-free at 15, 17, 18, 30 and 34 months from surgery.

Original languageEnglish
Pages (from-to)361-365
Number of pages5
JournalEuropean Journal of Surgical Oncology
Volume22
Issue number4
DOIs
Publication statusPublished - Jan 1 1996

Fingerprint

Skull Base
Neoplasms
Squamous Cell Carcinoma
Myocutaneous Flap
Superficial Back Muscles
Adenocarcinoma
Pneumocephalus
Rectus Abdominis
Maxillary Sinus
Intraoperative Complications
Maxilla
Chemoradiotherapy
Orbit
Eyelids
Nose
Length of Stay

Keywords

  • Facial tumours
  • Skull base
  • Surgery

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

Margarino, G., Scala, M., Mereu, P., Comandini, D., Schenone, G., Galli, A., ... Gipponi, M. (1996). Combined craniofacial approach to facial tumours involving the anterior skull base. European Journal of Surgical Oncology, 22(4), 361-365. https://doi.org/10.1016/S0748-7983(96)90264-4

Combined craniofacial approach to facial tumours involving the anterior skull base. / Margarino, G.; Scala, M.; Mereu, P.; Comandini, D.; Schenone, G.; Galli, A.; Francaviglia, N.; Gipponi, M.

In: European Journal of Surgical Oncology, Vol. 22, No. 4, 01.01.1996, p. 361-365.

Research output: Contribution to journalArticle

Margarino, G, Scala, M, Mereu, P, Comandini, D, Schenone, G, Galli, A, Francaviglia, N & Gipponi, M 1996, 'Combined craniofacial approach to facial tumours involving the anterior skull base', European Journal of Surgical Oncology, vol. 22, no. 4, pp. 361-365. https://doi.org/10.1016/S0748-7983(96)90264-4
Margarino, G. ; Scala, M. ; Mereu, P. ; Comandini, D. ; Schenone, G. ; Galli, A. ; Francaviglia, N. ; Gipponi, M. / Combined craniofacial approach to facial tumours involving the anterior skull base. In: European Journal of Surgical Oncology. 1996 ; Vol. 22, No. 4. pp. 361-365.
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