Combined depth imaging technique on spectral-domain optical coherence tomography

Giulio Barteselli, Dirk Uwe Bartsch, Sharif El-Emam, Maria Laura Gomez, Jay Chhablani, Su Na Lee, Laura Conner, William R. Freeman

Research output: Contribution to journalArticlepeer-review


Purpose: To describe a technique to obtain combined images of vitreoretinal and choroidal structures using spectral-domain (SD) optical coherence tomography (OCT) and to evaluate applicability in normal eyes and limitations in eyes with cataract. Design: Prospective, observational case series. Methods: Three different foveal scans, including conventional SD OCT, enhanced depth imaging OCT and the novel method called combined depth imaging (CDI) OCT, were obtained in 42 eyes of healthy volunteers and in 26 eyes with cataract using the Heidelberg Spectralis HRA (Heidelberg Engineering). The CDI OCT images were obtained manually using an image modification process that enhances the vitreoretinal interface first and then the choroid, while averaging 100 separate OCT scans. The visualization of the inner border of the preretinal pocket and the outer border of the choroid was graded by independent masked observers for each OCT scan method. Results: The CDI technique was able to create a good-quality combined image of the posterior structures in all the eyes, including eyes with cataract. The agreement between the grading performed by the independent observers was high for both the inner border of the vitreal pocket (κ, 0.86; P

Original languageEnglish
JournalAmerican Journal of Ophthalmology
Issue number4
Publication statusPublished - Apr 2013

ASJC Scopus subject areas

  • Ophthalmology


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