Abstract
The myocardial length-tension and the force-frequency relations are important mechanisms that regulate the contractile strength of the heart. Aims: To evaluate in humans the effect on left ventricular function of the interaction between the myocardial length-tension and force-frequency relations. Methods and results: Eight patients with dilated cardiomyopathy (DCM) and 6 control subjects underwent radionuclide monitoring of left ventricular function during atrial pacing, saline loading and atrial pacing at the end of saline loading. In controls, atrial pacing reduced left ventricular end-diastolic (P
Original language | English |
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Pages (from-to) | 727-735 |
Number of pages | 9 |
Journal | European Journal of Heart Failure |
Volume | 4 |
Issue number | 6 |
DOIs | |
Publication status | Published - Dec 2002 |
Keywords
- Contractility spectrum
- Heart failure
- Heart rate
- Myocardial infarction
- Pacing
- Ventricular function
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine