Combined kidney and liver transplantation for familial haemolytic uraemic syndrome

Giuseppe Remuzzi, Piero Ruggenenti, Daniela Codazzi, Marina Noris, Jessica Caprioli, Giuseppe Locatelli, Bruno Gridelli

Research output: Contribution to journalArticlepeer-review

Abstract

Recurrent haemolytic uraemic syndrome (HUS) is a genetic form of thrombotic microangiopathy that is mostly associated with low activity of complement factor H. The disorder usually develops in families, leads to end stage renal disease, and invariably recurs after kidney transplantation. We did a simultaneous kidney and liver transplantation in a 2-year-old child with HUS and a mutation in complement factor H to restore the defective factor H, with no recurrence of the disease. The operation was successful, and at discharge, the child had healthy kidney and liver function, with no sign of haemolysis.

Original languageEnglish
Pages (from-to)1671-1672
Number of pages2
JournalLancet
Volume359
Issue number9318
DOIs
Publication statusPublished - May 11 2002

ASJC Scopus subject areas

  • Medicine(all)

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