Combined liver and pancreatic islets transplantation in man using cyclosporin immunosuppression.

V. Mazzaferro, C. Socci, E. Regalia, S. Andreola, M. Di Bartolomeo, F. Bertuzzi, V. Di Carlo, G. Pozza, R. Doci, F. Bozzetti, L. Gennari

Research output: Contribution to journalArticlepeer-review

Abstract

We report a 1-year patient and graft survival after combined liver-pancreatic islet transplantation. The patient was affected by a pancreatic neuroendocrine carcinoma with extensive liver metastasis. Native pancreas and total liver removal was undertaken after a good response to chemotherapy, and the patient was still cancer-free 1 year later. Normal liver function and insulin independence was achieved, although islet response to glucose challenge remained delayed. Immunosuppression was maintained with cyclosporin monotherapy.

Original languageEnglish
JournalTransplant International
Volume7 Suppl 1
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Transplantation

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