Combined modality therapy for thoracic and head and neck cancers

A review of updated literature based on a consensus meeting

Pierfrancesco Franco, Alba Fiorentino, Francesco Dionisi, Michele Fiore, Silvia Chiesa, Stefano Vagge, Francesco Cellini, Luciana Caravatta, Mario Tombolini, Fiorenza De Rose, Icro Meattini, Gianluca Mortellaro, Giuseppina Apicella, Lorenza Marino, Daniela Greto

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Purpose: Combined modality therapy is a mainstay option for thoracic malignancies and head and neck cancers. The integration of different strategies is based on the multidisciplinary approach of modern clinical oncology. Radiation oncologists have to be educated, trained, and updated to provide state-of-the-art care to cancer patients and thus educational meetings are crucial. Methods: The Italian Association of Radiation Oncology Young Members Working Group (AIRO Giovani) organized its 8th national meeting, focused on combination therapy in lung, esophageal, and head and neck cancer (with a specific focus on larynx-preservation strategies for larynx/hypopharynx tumors), involving young professionals working in Italy. The meeting was addressed to young radiation oncologists, presenting state-of-the-art knowledge, based on the latest evidence in this field. We performed a review of the current literature based on the highlights of the Congress. Results: The multimodality approach of head and neck and thoracic malignancies includes surgery, chemotherapy, and radiotherapy, but also has to take into account new information and data coming from basic and translational research and including molecular biology, genetics, and immunology. All these aspects are crucial for the treatment of non-small-cell lung cancer and esophageal, esophagogastric junction, and larynx/hypopharynx malignancies. The integration of different treatments in the clinical decision-making process to combine therapies is crucial. Conclusions: Combination therapy has proved to be a consolidated approach in these specific oncologic settings, highlighting the importance of multimodality management in modern clinical oncology. Dedicated meetings on specific topics are helpful to improve knowledge and skills of young professionals in radiation oncology.

Original languageEnglish
Pages (from-to)459-471
Number of pages13
JournalTumori
Volume102
Issue number5
DOIs
Publication statusPublished - Sep 1 2016

Fingerprint

Combined Modality Therapy
Head and Neck Neoplasms
Thorax
Larynx
Hypopharynx
Radiation Oncology
Medical Oncology
Neoplasms
Molecular Biology
Therapeutics
Esophagogastric Junction
Translational Medical Research
Esophageal Neoplasms
Allergy and Immunology
Non-Small Cell Lung Carcinoma
Italy
Neck
Radiotherapy
Head
Drug Therapy

Keywords

  • Combined modality therapy
  • Esophageal cancer
  • Esophagogastric junction
  • Head and neck cancer
  • Lung cancer
  • Radiotherapy

ASJC Scopus subject areas

  • Medicine(all)
  • Oncology
  • Cancer Research

Cite this

Combined modality therapy for thoracic and head and neck cancers : A review of updated literature based on a consensus meeting. / Franco, Pierfrancesco; Fiorentino, Alba; Dionisi, Francesco; Fiore, Michele; Chiesa, Silvia; Vagge, Stefano; Cellini, Francesco; Caravatta, Luciana; Tombolini, Mario; De Rose, Fiorenza; Meattini, Icro; Mortellaro, Gianluca; Apicella, Giuseppina; Marino, Lorenza; Greto, Daniela.

In: Tumori, Vol. 102, No. 5, 01.09.2016, p. 459-471.

Research output: Contribution to journalReview article

Franco, P, Fiorentino, A, Dionisi, F, Fiore, M, Chiesa, S, Vagge, S, Cellini, F, Caravatta, L, Tombolini, M, De Rose, F, Meattini, I, Mortellaro, G, Apicella, G, Marino, L & Greto, D 2016, 'Combined modality therapy for thoracic and head and neck cancers: A review of updated literature based on a consensus meeting', Tumori, vol. 102, no. 5, pp. 459-471. https://doi.org/10.5301/tj.5000525
Franco, Pierfrancesco ; Fiorentino, Alba ; Dionisi, Francesco ; Fiore, Michele ; Chiesa, Silvia ; Vagge, Stefano ; Cellini, Francesco ; Caravatta, Luciana ; Tombolini, Mario ; De Rose, Fiorenza ; Meattini, Icro ; Mortellaro, Gianluca ; Apicella, Giuseppina ; Marino, Lorenza ; Greto, Daniela. / Combined modality therapy for thoracic and head and neck cancers : A review of updated literature based on a consensus meeting. In: Tumori. 2016 ; Vol. 102, No. 5. pp. 459-471.
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AU - Franco, Pierfrancesco

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AU - Dionisi, Francesco

AU - Fiore, Michele

AU - Chiesa, Silvia

AU - Vagge, Stefano

AU - Cellini, Francesco

AU - Caravatta, Luciana

AU - Tombolini, Mario

AU - De Rose, Fiorenza

AU - Meattini, Icro

AU - Mortellaro, Gianluca

AU - Apicella, Giuseppina

AU - Marino, Lorenza

AU - Greto, Daniela

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N2 - Purpose: Combined modality therapy is a mainstay option for thoracic malignancies and head and neck cancers. The integration of different strategies is based on the multidisciplinary approach of modern clinical oncology. Radiation oncologists have to be educated, trained, and updated to provide state-of-the-art care to cancer patients and thus educational meetings are crucial. Methods: The Italian Association of Radiation Oncology Young Members Working Group (AIRO Giovani) organized its 8th national meeting, focused on combination therapy in lung, esophageal, and head and neck cancer (with a specific focus on larynx-preservation strategies for larynx/hypopharynx tumors), involving young professionals working in Italy. The meeting was addressed to young radiation oncologists, presenting state-of-the-art knowledge, based on the latest evidence in this field. We performed a review of the current literature based on the highlights of the Congress. Results: The multimodality approach of head and neck and thoracic malignancies includes surgery, chemotherapy, and radiotherapy, but also has to take into account new information and data coming from basic and translational research and including molecular biology, genetics, and immunology. All these aspects are crucial for the treatment of non-small-cell lung cancer and esophageal, esophagogastric junction, and larynx/hypopharynx malignancies. The integration of different treatments in the clinical decision-making process to combine therapies is crucial. Conclusions: Combination therapy has proved to be a consolidated approach in these specific oncologic settings, highlighting the importance of multimodality management in modern clinical oncology. Dedicated meetings on specific topics are helpful to improve knowledge and skills of young professionals in radiation oncology.

AB - Purpose: Combined modality therapy is a mainstay option for thoracic malignancies and head and neck cancers. The integration of different strategies is based on the multidisciplinary approach of modern clinical oncology. Radiation oncologists have to be educated, trained, and updated to provide state-of-the-art care to cancer patients and thus educational meetings are crucial. Methods: The Italian Association of Radiation Oncology Young Members Working Group (AIRO Giovani) organized its 8th national meeting, focused on combination therapy in lung, esophageal, and head and neck cancer (with a specific focus on larynx-preservation strategies for larynx/hypopharynx tumors), involving young professionals working in Italy. The meeting was addressed to young radiation oncologists, presenting state-of-the-art knowledge, based on the latest evidence in this field. We performed a review of the current literature based on the highlights of the Congress. Results: The multimodality approach of head and neck and thoracic malignancies includes surgery, chemotherapy, and radiotherapy, but also has to take into account new information and data coming from basic and translational research and including molecular biology, genetics, and immunology. All these aspects are crucial for the treatment of non-small-cell lung cancer and esophageal, esophagogastric junction, and larynx/hypopharynx malignancies. The integration of different treatments in the clinical decision-making process to combine therapies is crucial. Conclusions: Combination therapy has proved to be a consolidated approach in these specific oncologic settings, highlighting the importance of multimodality management in modern clinical oncology. Dedicated meetings on specific topics are helpful to improve knowledge and skills of young professionals in radiation oncology.

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