Combined ultrasound–CT approach to monitor acute exacerbation of interstitial lung disease

Silvia Mongodi, Andrea Colombo, Anita Orlando, Lorenzo Cavagna, Bélaid Bouhemad, Giorgio Antonio Iotti, Francesco Mojoli

Research output: Contribution to journalArticlepeer-review


Background: Lung ultrasound is a bedside non-irradiating tool for assessment and monitoring of lung diseases. A lung ultrasound score based on visualized artefacts allows reliable quantification of lung aeration, and is useful to monitor mechanical ventilation setting, fluid resuscitation and antibiotic response in critical care. In the context of interstitial lung diseases associated to connective tissue disorders, lung ultrasound has been integrated to computed tomography for diagnosis and follow-up monitoring of chronic lung disease progression. Case presentation: This case describes a severe acute exacerbation of interstitial lung disease associated to dermatomyositis–polymyositis requiring prolonged extra-corporeal life support. Lung ultrasound score was performed daily and allowed monitoring and guiding both the need of advanced imaging as computed tomography and immunosuppressive therapy. Conclusions: This case suggests lung ultrasound may be a useful monitoring tool for the response to immunosuppressive therapy in acute severe rheumatic interstitial lung disease, where chest X-ray is poorly informative, and transportation is at high risk.

Original languageEnglish
Article number27
JournalUltrasound Journal
Issue number1
Publication statusPublished - Dec 1 2020


  • ECMO
  • High-resolution CT
  • Interstitial lung disease
  • Lung monitoring
  • Lung ultrasound

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


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