Combined use of skin needling and platelet-rich plasma in acne scarring treatment

Gabriella Fabbrocini, Valerio De Vita, Francesco Pastore, Luigia Panariello, Nunzio Fardella, Rossana Sepulveres, Elio D'Agostino, Norma Cameli, Antonella Tosti

Research output: Contribution to journalArticlepeer-review


Platelet-rich plasma (PRP) contains autologous growth factors, which could act synergistically with growth factors induced by skin needling in order to enhance the wound-healing response. The combination of treatments, carried out by using skin needling and PRP application, should enhance both efficacy of skin needling and PRP application. The objective of this study is to establish the effectiveness of the combined use of skin needling and PRP application in acne scarring treatment. Twelve patients affected with rolling acne scars were enrolled. Each patient underwent 2 sessions of treatments, each consisting of skin needling followed by PRP application on the right side of the face and skin needling alone on the left side of the face. Digital photographs of all patients were taken. Photographic data were analyzed by using the Sign Test (α

Original languageEnglish
Pages (from-to)177-183
Number of pages7
JournalCosmetic Dermatology
Issue number4
Publication statusPublished - Apr 2011

ASJC Scopus subject areas

  • Dermatology
  • Surgery


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