Combining near infrared spectroscopy and functional MRI during continuous performance test in healthy subjects

Michele Butti, Aurora Pastori, Anna Merzagora, Anna Bianchi, Alessandra Bardoni, Vincenzo Branca, Antonella Costa, Sergio Cerutti, Gianluigi Reni

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The study of cognitive functions is a major challenge of the modern functional imaging. Activation of specific cerebral area is obtained from the observation of physic characteristic affected by changes occurring in the blood flow resulting from an increased metabolic consumption. In this work two imaging techniques are used, the functional magnetic resonance (fMRI) and the Near Infrared Spectroscopy (NIRS), in order to assess cerebral performance during the execution of a well known sustained attention task, the Conners' Continuous Performance Test (CPT). With fMRI analysis were found activations in the frontal, parietal and supplementary motor areas, whereas NIRS system showed a region-wise difference in the variations of parameters and different activation trend localized in the middle-right frontal area. The combined analysis of the two techniques allows to obtain more detailed information and places itself as a first step toward a result of multimodal image integration.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages1944-1947
Number of pages4
DOIs
Publication statusPublished - 2006
Event28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 - New York, NY, United States
Duration: Aug 30 2006Sep 3 2006

Other

Other28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
CountryUnited States
CityNew York, NY
Period8/30/069/3/06

ASJC Scopus subject areas

  • Bioengineering

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