Communication and pragmatic breakdowns in amyotrophic lateral sclerosis patients

Valentina Bambini, Giorgio Arcara, Ilaria Martinelli, Sara Bernini, Elena Alvisi, Andrea Moro, Stefano Cappa, Mauro Ceroni

Research output: Contribution to journalArticle

Abstract

While there is increasing attention toward cognitive changes in amyotrophic lateral sclerosis (ALS), the domain of pragmatics, defined as the ability to integrate language and context to engage in successful communication, remains unexplored. Here we tested pragmatic abilities in 33 non-demented ALS patients and 33 healthy controls matched for age and education through 6 different tasks, ranging from discourse organization to the comprehension of figurative language, further grouped in three composite measures for pragmatic production, pragmatic comprehension and global pragmatic abilities. For a subgroup of patients, assessment included executive functions and social cognition skills. ALS patients were impaired on all pragmatic tasks relative to controls, with 45% of the patients performing below cut-off in at least one pragmatic task, and 36% impaired on the global pragmatic score. Pragmatic breakdowns were more common than executive deficit as defined by the consensus criteria, and approximately as prevalent as deficits in social cognition. Multiple regression analyses support the idea of an interplay of executive and social cognition abilities in determining the pragmatic performance, although all these domains show some degree of independence. These findings shed light on pragmatic impairment as a relevant dimension of ALS, which deserves further consideration in defining the cognitive profile of the disease, given its vital role for communication and social interaction in daily life.

Original languageEnglish
Pages (from-to)1-12
Number of pages12
JournalBrain and Language
Volume153-154
DOIs
Publication statusPublished - Feb 1 2016

Fingerprint

Amyotrophic Lateral Sclerosis
Aptitude
pragmatics
Communication
Cognition
communication
Language
social cognition
Executive Function
Interpersonal Relations
Consensus
ability
Regression Analysis
Education
deficit
comprehension
Social Cognition
language
Social Skills
Disease

Keywords

  • Amyotrophic lateral sclerosis
  • Communication
  • Discourse
  • Metaphor
  • Neuropragmatics
  • Pragmatics
  • Social cognition

ASJC Scopus subject areas

  • Linguistics and Language
  • Speech and Hearing
  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience
  • Language and Linguistics

Cite this

Communication and pragmatic breakdowns in amyotrophic lateral sclerosis patients. / Bambini, Valentina; Arcara, Giorgio; Martinelli, Ilaria; Bernini, Sara; Alvisi, Elena; Moro, Andrea; Cappa, Stefano; Ceroni, Mauro.

In: Brain and Language, Vol. 153-154, 01.02.2016, p. 1-12.

Research output: Contribution to journalArticle

Bambini, V, Arcara, G, Martinelli, I, Bernini, S, Alvisi, E, Moro, A, Cappa, S & Ceroni, M 2016, 'Communication and pragmatic breakdowns in amyotrophic lateral sclerosis patients', Brain and Language, vol. 153-154, pp. 1-12. https://doi.org/10.1016/j.bandl.2015.12.002
Bambini V, Arcara G, Martinelli I, Bernini S, Alvisi E, Moro A et al. Communication and pragmatic breakdowns in amyotrophic lateral sclerosis patients. Brain and Language. 2016 Feb 1;153-154:1-12. https://doi.org/10.1016/j.bandl.2015.12.002
Bambini, Valentina ; Arcara, Giorgio ; Martinelli, Ilaria ; Bernini, Sara ; Alvisi, Elena ; Moro, Andrea ; Cappa, Stefano ; Ceroni, Mauro. / Communication and pragmatic breakdowns in amyotrophic lateral sclerosis patients. In: Brain and Language. 2016 ; Vol. 153-154. pp. 1-12.
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