TY - JOUR
T1 - Comorbidities of sleep disorders in childhoodand adolescence
T2 - Focus on migraine
AU - Dosi, Claudia
AU - Riccioni, Assia
AU - Corte, Martina Della
AU - Novelli, Luana
AU - Ferri, Raffaele
AU - Bruni, Oliviero
PY - 2013
Y1 - 2013
N2 - The correlation and/or comorbidity between sleep disorders and headache has been reported in numerous studies, but the exact nature of the association between headache, disordered sleep, and underlying mechanisms remains poorly understood. The bidirectional association between sleep and headache is mediated by a temporal link (headache occurs during sleep, after sleep, and in relationship with sleep stages), by a quantitative relationship (excess, lack, bad quality, short duration of sleep may trigger headache), and by a reciprocal connection (headache may cause sleep disruption and may be associated with several sleep disturbances). This association is most evident for primary headache disorders, especially in childhood. A congenital alteration of neurotransmitter pathways (serotoninergic and dopaminergic) might predispose individuals to both disorders, presenting as sleep-wake rhythm disorder in infancy or as headache disorder later in childhood, as result of this neurotransmitter imbalance. Clinicians should be aware that a complete clinical evaluation of childhood headache includes a careful sleep history, taking into account that the treatment of sleep disturbances could lead to an improvement of headache symptoms and vice versa.
AB - The correlation and/or comorbidity between sleep disorders and headache has been reported in numerous studies, but the exact nature of the association between headache, disordered sleep, and underlying mechanisms remains poorly understood. The bidirectional association between sleep and headache is mediated by a temporal link (headache occurs during sleep, after sleep, and in relationship with sleep stages), by a quantitative relationship (excess, lack, bad quality, short duration of sleep may trigger headache), and by a reciprocal connection (headache may cause sleep disruption and may be associated with several sleep disturbances). This association is most evident for primary headache disorders, especially in childhood. A congenital alteration of neurotransmitter pathways (serotoninergic and dopaminergic) might predispose individuals to both disorders, presenting as sleep-wake rhythm disorder in infancy or as headache disorder later in childhood, as result of this neurotransmitter imbalance. Clinicians should be aware that a complete clinical evaluation of childhood headache includes a careful sleep history, taking into account that the treatment of sleep disturbances could lead to an improvement of headache symptoms and vice versa.
KW - Adolescence
KW - Childhood
KW - Headache
KW - Migraine
KW - Sleep
UR - http://www.scopus.com/inward/record.url?scp=84879292658&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84879292658&partnerID=8YFLogxK
U2 - 10.2147/NSS.S34840
DO - 10.2147/NSS.S34840
M3 - Article
C2 - 23788845
AN - SCOPUS:84879292658
VL - 5
SP - 77
EP - 85
JO - Nature and Science of Sleep
JF - Nature and Science of Sleep
SN - 1179-1608
ER -