Comparative analysis of the human dystrophin and utrophin gene structures

Research output: Contribution to journalArticle

Abstract

We present analysis of intronic sequences in the human DMD and UTRN genes. In both genes accumulation of repeated elements could account for intron expansion. Out-of-frame rod-domain exons have stronger splice sites and are separated by significantly longer introns as compared to in-frame exons. These features are unique for the two homologs and not shared by other spectrin superfamily genes.

Original languageEnglish
Pages (from-to)793-798
Number of pages6
JournalGenetics
Volume160
Issue number2
Publication statusPublished - 2002

    Fingerprint

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

Cite this