Valutazione comparativa della attività antibatterica del cefotaxime e della cefalotina mediante un sistema elettronico computerizzato.

Translated title of the contribution: Comparative evaluation of the antibacterial activity of cefotaxime and cephalotin by using an automated antimicrobial susceptibility determination system

E. Concia, P. Marone, C. Dos Santos, L. Bono

Research output: Contribution to journalArticlepeer-review

Abstract

Cefotaxime is a new broad-spectrum injectable cephalosporin which is stable to most beta-lactamases. In this study we have evaluated the antibacterial activity of cefotaxime comparatively with the activity of cephalotin against 66 Gram-negative bacteria and 31 Gram-positive bacteria by using an automated antimicrobial susceptibility determination system. Cefotaxime was markedly more active than cephalotin against Klebsiella pneumoniae, Proteus, Enterobacter, Escherichia coli and Serratia. Against Gram-positive clinical isolates cefotaxime was less active than cephalotin. Regrowth was observed mainly with cephalotin against Gram-negative clinical isolates, therefore the results obtained after a few hours with automated system should be carefully interpreted.

Translated title of the contributionComparative evaluation of the antibacterial activity of cefotaxime and cephalotin by using an automated antimicrobial susceptibility determination system
Original languageItalian
Pages (from-to)223-232
Number of pages10
JournalQuaderni Sclavo di diagnostica clinica e di laboratorio
Volume18
Issue number2
Publication statusPublished - Jun 1982

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Comparative evaluation of the antibacterial activity of cefotaxime and cephalotin by using an automated antimicrobial susceptibility determination system'. Together they form a unique fingerprint.

Cite this