Comparative evaluation of the Bruker Biotyper and Vitek MS matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass Spectrometry systems for identification of yeasts of medical importance

Nicasio Mancini, Elena De Carolis, Laura Infurnari, Antonietta Vella, Nicola Clementi, Luisa Vaccaro, Alberto Ruggeri, Brunella Posteraro, Roberto Burioni, Massimo Clementi, Maurizio Sanguinetti

Research output: Contribution to journalArticle

Abstract

We report the first comparative evaluation between the Bruker Biotyper MS (BMS) and the Vitek MS (VMS) for the identification of yeasts. The rate of correct identifications at the species level was comparable using the commercial databases (89.8% versus 84.3%; P = 0.712), but higher for BMS using an in-house-extended database (100% versus 84.3%; P = 0.245). Importantly, the rate of misidentification was significantly higher for VMS (1% versus 12.1%; P <0.0001), including the rate of major errors (0% versus 4.5%; P = 0.0036).

Original languageEnglish
Pages (from-to)2453-2457
Number of pages5
JournalJournal of Clinical Microbiology
Volume51
Issue number7
DOIs
Publication statusPublished - 2013

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ASJC Scopus subject areas

  • Microbiology (medical)
  • Medicine(all)

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