Comparative long term effects of nebivolol and carvedilol in hypertensive heart failure patients

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Background: Beta-blockers improve left ventricular (LV) systolic function and prognosis in patients with chronic heart failure (CHF), but their different pleiotropic properties may influence their cardiovascular effects. This open-label study compared the effects of long-term treatment with nebivolol versus carvedilol on LV ejection fraction (LVEF), in hypertensive CHF patients. Secondary end points were to assess the effect of the 2 beta-blockers on exercise capacity and clinical outcome. Methods and Results: A total of 160 hypertensive CHF patients, with LVEF

Original languageEnglish
Pages (from-to)703-709
Number of pages7
JournalJournal of Cardiac Failure
Issue number9
Publication statusPublished - Sep 2011



  • Beta-adrenergic receptor blocker
  • heart failure
  • hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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