Comparative population analysis of Klebsiella pneumoniae strains with extended-spectrum β-lactamases colonizing patients in rehabilitation centers in four countries

A. Baraniak, R. Izdebski, J. Fiett, E. Sadowy, A. Adler, M. Kazma, J. Salomon, C. Lawrence, A. Rossini, A. Salvia, J. Vidal Samso, J. Fierro, M. Paul, Y. Lerman, S. Malhotra-Kumar, C. Lammens, H. Goossens, W. Hryniewicz, C. Brun-Buisson, Y. CarmeliM. Gniadkowski

Research output: Contribution to journalArticlepeer-review

Abstract

The international project MOSAR was conducted in five rehabilitation centers; patients were screened for rectal carriage of extended-spectrum β-lactamase (ESBL)-producing members of the Enterobacteriaceae. Among 229 Klebsiella pneumoniae isolates, four clonal groups (CG) or complexes (CC) prevailed: CG17 in France, CG101 in Italy, CG15 in Spain, and CC147 in Israel. ESBLs, mainly CTX-Ms, were produced by 226 isolates; three isolates expressed AmpC-like cephalosporinases. High genetic diversity of K. pneumoniae populations was observed, with specific characteristics at each center.

Original languageEnglish
Pages (from-to)1992-1997
Number of pages6
JournalAntimicrobial Agents and Chemotherapy
Volume57
Issue number4
DOIs
Publication statusPublished - Apr 2013

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology
  • Infectious Diseases

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