Comparative study of the thromboresistance of Dacron® combined with various polyurethanes

D. L. Leake, E. Cenni, D. Cavedagna, S. Stea, G. Ciapetti, A. Pizzoferrato

Research output: Contribution to journalArticlepeer-review

Abstract

In vitro tests were carried out on Dacron® samples differently knitted and on Dacron® vascular prostheses coated with various urethanes. All the materials were put in contact with human platelet-rich plasma; the subsequent assay of three platelet released substances, i.e. β-thromboglobulin, platelet factor 4 and thromboxane B2, as well as the quantification of platelet retention, were used to establish the degree of thrombogenicity of the material itself. In some cases Dacron®-urethanes composites showed better thromboresistance than any other materials conventionally used in vascular surgery.

Original languageEnglish
Pages (from-to)441-444
Number of pages4
JournalBiomaterials
Volume10
Issue number7
DOIs
Publication statusPublished - 1989

Keywords

  • Dacron®
  • platelets
  • release reaction
  • Thrombogenicity

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

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